2. 抗体抑制剂
  3. 动物体内抗体
  4. Anti-Mouse VISTA Antibody (13F3)

Anti-Mouse VISTA Antibody (13F3) 

目录号: HY-P990145 纯度: ≥95.0%
COA 技术支持

Anti-Mouse VISTA Antibody (13F3) 是一种抗小鼠 VISTA IgG 单克隆抗体。Anti-Mouse VISTA Antibody (13F3) 可以通过阻断其与配体如 VSIG3 的结合来逆转 VISTA 的免疫抑制作用。Anti-Mouse VISTA Antibody (13F3) 通过促进 Th17 细胞分化加剧肺纤维化 (PF)。Anti-Mouse VISTA Antibody (13F3) 可用于癌症如乳腺癌和肺纤维化的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Anti-Mouse VISTA Antibody (13F3)

Anti-Mouse VISTA Antibody (13F3) Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥2200
In-stock
5 mg 现货 询价
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Anti-Mouse VISTA Antibody (13F3) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse VISTA Antibody (13F3) is an anti-mouse VISTA IgG monoclonal antibody. Anti-Mouse VISTA Antibody (13F3) can reverse the immunosuppressive effect of VISTA by blocking its binding to ligands such as VSIG3. Anti-Mouse VISTA Antibody (13F3) exacerbates pulmonary fibrosis (PF) by promoting Th17 cell differentiation. Anti-Mouse VISTA Antibody (13F3) can be used for research on cancer such as breast cancer and PF[1][2].

同型

Armenian hamster IgG
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

VISTA
体内研究
(In Vivo)

Anti-Mouse VISTA Antibody (13F3) (50 μg，肿瘤内注射，第 7、9、12、14 和 16 天) 显著抑制了携带 4T1 肿瘤的 Balb/c 小鼠的肿瘤生长[1]。
Anti-Mouse VISTA Antibody (13F3) (腹腔注射，每 3 天一次，从第 7 天到第 21 天) 在 Bleomycin hydrochloride (BLM) (HY-17565A) 诱导的肺纤维化 (PF) 模型中加重 C57BL/6 小鼠的肺纤维化[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 2×104 4T1 cells injected Balb/c mice[1]
Dosage: 50 μg
Administration: intratumoral injection, on day 7, 9, 12, 14 and 16
Result: Significantly inhibited tumor volume (inhibition rate of 53%).
基因 ID

74048  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (268 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Anti-Mouse VISTA Antibody (13F3) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse VISTA Antibody (13F3)VISTAPF4T1Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Anti-Mouse VISTA Antibody (13F3)
目录号：
HY-P990145
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z