2. Immunology/Inflammation
  3. Transmembrane Glycoprotein
  4. Anti-Rat CD8α Antibody (OX-8)

Anti-Rat CD8α Antibody (OX-8) 

目录号: HY-P990126
技术支持

Anti-Rat CD8α Antibody (OX-8) 是一种抗大鼠 CD8α IgG1 单克隆抗体。Anti-Rat CD8α Antibody (OX-8) 可耗竭 CD8+ T 细胞。Anti-Rat CD8α Antibody (OX-8) 可增强气道重塑。Anti-Rat CD8α Antibody (OX-8) 可用于研究过敏性疾病和感染，如 RHV-rn1 病毒感染和哮喘。

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Anti-Rat CD8α Antibody (OX-8)

Anti-Rat CD8α Antibody (OX-8) Chemical Structure

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Anti-Rat CD8α Antibody (OX-8) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Rat CD8α Antibody (OX-8) is an anti-rat CD8α IgG1 monoclonal antibody. Anti-Rat CD8α Antibody (OX-8) can deplete CD8+ T cells. Anti-Rat CD8α Antibody (OX-8) can enhance airway remodeling. Anti-Rat CD8α Antibody (OX-8) can be used for researches on allergic conditions and infections such as RHV-rn1 virus infection and asthma[1][2].

同型

Mouse IgG1 kappa
推荐同型对照抗体
反应种属

Rat
IC50 & Target

CD8α
体内研究
(In Vivo)

Anti-Rat CD8α Antibody (OX-8) (0.2-0.5 mg，静脉注射，第 -2、5 和 12 天) 显著延长了 RHV-rn1 病毒感染模型 Lewis 大鼠的病毒血症持续时间[1]。
Anti-Rat CD8α Antibody (OX-8) (250 μg，腹腔注射，第 13、19 和 25 天) 显著增强了 Ovalbumin (OVA) (HY-W250978) 诱导的哮喘雄性棕色挪威大鼠的气道重塑[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Lewis rats (7-8 weeks) with a RHV-rn1 virus infection model[1]
Dosage: 0.5 mg for first-dose, 0.2 mg for subsequent doses
Administration: Intravenous injection (i.v.), on day -2, 5 and 12
Result: Significantly prolonged the duration of viral infection.
Decreased the number of CD8+ T cells.
Animal Model: OVA (1 mg) induced male Brown Norway rats (6-7 weeks)[2]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), on day 13, 19 and 25
Result: Increased PCNA positive cells.
Increased PAS positive cells.
Increased the positive area of α-SMA.
基因 ID

12525  [NCBI]

Accession

P01731-1
分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Rat CD8α Antibody (OX-8) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Rat CD8α Antibody (OX-8)Transmembrane GlycoproteinCD8αT cellsasthmaRHV-rn1Inhibitorinhibitorinhibit

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