2. Anti-infection
  3. Bacterial Parasite
  4. Antimycobacterial agent-4

Antimycobacterial agent-4 

目录号: HY-148180 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Antimycobacterial agent-4 是一种 2-氨基-4-(2-吡啶基) 噻唑衍生物，对结核分枝杆菌 H37Rv 菌株具有抗微生物活性和抗疟原虫活性，对哺乳动物细胞系具有细胞毒性。

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Antimycobacterial agent-4 Chemical Structure

Antimycobacterial agent-4 Chemical Structure

CAS No. : 476319-66-1

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1 mg ￥1200
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5 mg ￥2600
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10 mg ￥4200
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Antimycobacterial agent-4 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2].

IC50 & Target

Plasmodium

 

体外研究
(In Vitro)

Antimycobacterial agent-4 (compound 12) exerts antimycobacterial activity against the Mycobacterium tuberculosis H37Rv strain (MIC99=5 μM), and antiplasmodial activity against the Chloroquine (HY-17589A) sensitive NF54 Plasmodium falciparum strain (IC50=6.1 μM) and cytotoxicity on a mammalian cell line (CHO, IC50=2.2 μM)[1].
Antimycobacterial agent-4 (compound 38) shows cytotoxicity against Vero cells with toxic concentration TC50 of 3.0 μM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antimycobacterial agent-4 相关抗体:
分子量

326.33

Formula

C15H10N4O3S
CAS 号
性状

固体

颜色

Off-white to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

COA (192 KB) HNMR (153 KB)

产品使用指南 (1538 KB)
参考文献

Antimycobacterial agent-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimycobacterial agent-4476319-66-1Antimycobacterial agent4Antimycobacterial agent 4BacterialParasite2-amino-4-(2-pyridyl) thiazoleantimycobacterialantiplasmodialcytotoxicitychloroquine sensitiveNF54 strainH37Rv strainInhibitorinhibitorinhibit

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