1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. Axatilimab

Axatilimab  (Synonyms: SNDX-6352)

目录号: HY-P99452 纯度: 99.59%
COA

Axatilimab (SNDX-6352) 是一种人源 IgG4 抗体,对 CSF-1R 具有高亲和力。Axatilimab 可用于慢性移植物抗宿主病 (cGVHD) 和肿瘤疾病的研究。

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Axatilimab Chemical Structure

Axatilimab Chemical Structure

CAS No. : 2155851-88-8

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg ¥7800
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases[1][2].

体外研究
(In Vitro)

Axatilimab (SNDX-6352) 通过与 CSF-1R 结合并阻断其两种已知配体 CSF-1 和 IL-34 的激活来影响单核细胞和巨噬细胞的迁移、增殖、分化和存活。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Axatilimab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Axatilimab
目录号:
HY-P99452
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