2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. Antibody-Drug Conjugates (ADCs) Topoisomerase
  4. AZD0516

AZD0516 是一款靶向前列腺六跨膜上皮抗原 2 (STEAP2) 的首创抗体-药物偶联物 (ADC)。由 抗 STEAP2 单克隆抗体 (mAb) 通过链间半胱氨酸与马来酰亚胺反应性、β-葡萄糖醛酸酶可裂解的连接子 (HY-173635) 和拓扑异构酶 1 抑制剂 Exatecan (HY-13631) 偶联而成。AZD0516 可用于前列腺癌的研究。

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AZD0516 Chemical Structure

AZD0516 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货
1 mg ￥10880
询问价格 & 货期
5 mg 现货 询问价格 & 货期

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AZD0516 相关抗体

Top Publications Citing Use of Products

查看 Topoisomerase 亚型特异性产品:

查看所有亚型
Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZD0516 is a first-in-class antibody-drug conjugate (ADC) targeting six-transmembrane epithelial antigen of the prostate-2 (STEAP2). The anti-STEAP2 monoclonal antibody (mAb) is conjugated via interchain cysteines to a maleimide-reactive, β-glucuronidase-cleavable linker (HY-173635) bearing the topoisomerase 1 inhibitor, Exatecan (HY-13631). AZD0516 can be used for the study of prostate cancer[1].

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AZD0516 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZD0516AZD 0516AZD-0516Antibody-Drug Conjugates (ADCs)TopoisomeraseAntibody-Drug ConjugatesSTEAP2ADCprostate cancerInhibitorinhibitorinhibit

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产品名称：
AZD0516
目录号：
HY-173639
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