Topoisomerase Inhibitors

Topoisomerase

Topo I

Topo II

Topoisomerase Inhibitors & Agonists

Product Name	Topoisomerase	Topo I	Topo II	Purity
Doxorubicin hydrochloride		Topoisomerase I, IC₅₀: 0.8 μM	Topoisomerase II, IC₅₀: 2.67 μM	99.90%
Etoposide			Topoisomerase II	99.94%
Exatecan mesylate		Topoisomerase I, IC₅₀: 0.975 μg/mL		99.92%
Dxd		Topoisomerase I, IC₅₀: 0.31 μM		≥99.0%
SN-38		Topoisomerase I		99.89%
Irinotecan		Topoisomerase I		99.84%
Camptothecin		Topoisomerase I, IC₅₀: 679 nM		99.82%
Topotecan hydrochloride		Topoisomerase I		99.76%
Daunorubicin hydrochloride			Topoisomerase II	99.62%
Mitoxantrone			Topoisomerase II	98.36%
Exatecan		Topoisomerase I, IC₅₀: 2.2 μM		99.93%
Irinotecan hydrochloride		Topoisomerase I		99.89%
Epirubicin hydrochloride	Topoisomerase			99.16%
Levofloxacin	TOPO IV			99.93%
Betulinic acid		Topoisomerase I, IC₅₀: 5 μM		≥98.0%
Idarubicin hydrochloride			Topoisomerase II	99.94%
Mitoxantrone dihydrochloride			Topoisomerase II	99.55%
β-Lapachone		Topoisomerase I		99.99%
Teniposide			Topoisomerase II	98.88%
Pirarubicin			Topoisomerase II	99.61%
Aldoxorubicin			Topoisomerase II
Irinotecan hydrochloride trihydrate		Topoisomerase I		99.89%
Datopotamab deruxtecan		Topoisomerase I		99.54%
Banoxantrone dihydrochloride			Topoisomerase II	99.67%
PNU-159682		Topoisomerase I		98.25%
Dxd-d₅		Topoisomerase I, IC₅₀: 0.31 μM		98.76%
Belotecan hydrochloride		Top1		99.88%
(S)-10-Hydroxycamptothecin		Topoisomerase I		99.38%
Proscillaridin A		Topoisomerase I, IC₅₀: 30 nM	Topoisomerase II, IC₅₀: 100 nM	99.74%
Aurintricarboxylic acid			Topoisomerase II
Bisantrene			Topoisomerase II	98.08%
Etoposide phosphate			Topoisomerase II
Nalidixic acid	Topoisomerase			99.97%
Pirarubicin Hydrochloride			Topoisomerase II	98.56%
Amsacrine			Topoisomerase II	99.95%
Pixantrone			Topoisomerase II	98.38%
Aclacinomycin A		Topoisomerase I	Topoisomerase II	98.95%
Levofloxacin hydrate	TOPO IV			99.93%
Chloroquinoxaline sulfonamide			topoisomerase II alpha topoisomerase II beta	99.06%
Gatifloxacin			Topoisomerase II, IC₅₀: 36.7 μM	99.55%
Ellipticine hydrochloride			Topoisomerase II	99.34%
Coralyne chloride		Topoisomerase I		99.34%
Hycanthone		Topoisomerase I	Topoisomerase II	99.97%
Aclacinomycin A hydrochloride		Topoisomerase I	Topoisomerase II
PluriSIn #2			topoisomerase II alpha	≥98.0%
Indotecan		Topoisomerase I		≥98.0%
TAS-103 dihydrochloride		Topoisomerase I	Topoisomerase II	98.87%
Amonafide			Topoisomerase II	99.92%
Genz-644282		Topoisomerase I		99.53%
Amsacrine hydrochloride			Topoisomerase II	99.98%
Gatifloxacin hydrochloride			Topoisomerase II, : 36.7 μM	99.94%
(±)-10-Hydroxycamptothecin		Topoisomerase I		99.44%
Daun02	Topoisomerase			98.72%
Amrubicin			Topoisomerase II	≥98.0%
9-Aminocamptothecin		Topoisomerase I		99.05%
Voreloxin Hydrochloride			Topoisomerase II	99.96%
Karenitecin		Topoisomerase I		98.27%
MC-DOXHZN hydrochloride			Topoisomerase II	≥98.0%
Ellipticine			Topoisomerase II	98.17%
Garenoxacin Mesylate hydrate	TOPO IV, IC₅₀: 1.5-2.5 μg/mL			99.78%
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan		Topoisomerase I
Flumequine			Topoisomerase II, IC₅₀: 15 μM	99.89%
Intoplicine		Topoisomerase I	Topoisomerase II	98.36%
(±)-Evodiamine		Top1		99.97%
Gimatecan		Topoisomerase I		99.28%
Groenlandicine		Topoisomerase I		99.87%
Lurtotecan		Topoisomerase I		98.01%
LMP744 hydrochloride		Top1		99.70%
MC-GGFG-AM-(10Me-11F-Camptothecin)		Topoisomerase I		98.06%
Levofloxacin hydrochloride	TOPO IV			≥98.0%
Isodiospyrin		Topoisomerase I		99.77%
Indimitecan		Top1		98.03%
Topotecan		Topoisomerase I
Podocarpusflavone A		Topoisomerase I, IC₅₀: 119.425 μM		98.69%
Seconeolitsine		Topoisomerase I, IC₅₀: 17 μM
Zabofloxacin hydrochloride		Topoisomerase I	Topoisomerase II	98.06%
Namitecan		Topoisomerase I		99.25%
ARN-21934			topoisomerase II alpha topoisomerase II beta	98.02%
Doxorubicin		Topoisomerase I, IC₅₀: 0.8 μM	Topoisomerase II, IC₅₀: 2.67 μM
CH-0793076		Topoisomerase I, IC₅₀: 2.3 μM
Zabofloxacin		Topoisomerase I	Topoisomerase II	98.02%
Edotecarin		Topoisomerase I, IC₅₀: 50 nM		98.39%
CH-0793076 TFA		Topoisomerase I, IC₅₀: 2.3 μM		98.71%
SW044248		Topoisomerase I		99.60%
LMP744		Top1
Pixantrone free base			Topoisomerase II
Daunorubicin			Topoisomerase II
TAS-103		Topoisomerase I	Topoisomerase II
MC-DOXHZN			Topoisomerase II
Exatecan mesylate dihydrate		Topoisomerase I, IC₅₀: 2.2 μM
Topotecan hydrochloride hydrate		Topoisomerase I
Rebeccamycin		Topoisomerase I
Gatifloxacin sesquihydrate			Topoisomerase II, IC₅₀: 36.7 μM
Etoposide phosphate disodium			Topoisomerase II
Antitumor agent-63		Top1
Daunorubicin citrate			Topoisomerase II
Mitoxantrone diacetate			Topoisomerase II
Topoisomerase II inhibitor 8			Topoisomerase II, IC₅₀: 0.52 μM
ZLHQ-5f		Top1
Razoxane			Topoisomerase II	99.16%
Topoisomerase IIα-IN-4			topoisomerase II alpha, IC₅₀: 3.8 μM topoisomerase II beta, IC₅₀: 10.1 μM
Topoisomerase II inhibitor 13			Topoisomerase II	99.26%
Topoisomerase II/EGFR-IN-1			Topoisomerase II
Topoisomerase II inhibitor 5			Topoisomerase II
Niranthin	Topoisomerase
MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan		Topoisomerase I
Topoisomerase IV inhibitor 1	TOPO IV, IC₅₀: 0.23 μM
Corydamine		Topoisomerase I	Topoisomerase II
Nalidixic acid sodium salt	Topoisomerase			99.74%
Elomotecan hydrochloride		Topoisomerase I	Topoisomerase II
CS1			topoisomerase II alpha
Topoisomerase I inhibitor 3		Topoisomerase I
BNS-22			topoisomerase II alpha, IC₅₀: 2.8 μM (in human) topoisomerase II beta, IC₅₀: 0.42 μM (in human)
T-2513 hydrochloride		Topoisomerase I
Topoisomerase II inhibitor 11			Topoisomerase II, IC₅₀: 2.89 μM
Topoisomerase II inhibitor 4			Topoisomerase II
Topoisomerase I inhibitor 12		Topoisomerase I
Gly-Cyclopropane-Exatecan		Topoisomerase I
Huanglongmycin N		Topoisomerase I, EC₅₀: 14 μM
Elomotecan		Topoisomerase I	Topoisomerase II
Topoisomerase IIα-IN-5			topoisomerase II alpha
Topoisomerase II inhibitor 9			Topoisomerase II, IC₅₀: 0.97 μM
Topoisomerase IIα-IN-2			topoisomerase II alpha topoisomerase II beta
Topo I-IN-1		Topoisomerase I
Anti-MRSA agent 7	TOPO IV, IC₅₀: 0.059 μM (E. coli ) TOPO IV, IC₅₀: 0.341 μM (S. aureus)
TP0480066			Topoisomerase II
Topo I/COX-2-IN-1		Topoisomerase I, IC₅₀: 4.42 μM
Topoisomerase I/II inhibitor 3		Topoisomerase I	Topoisomerase II
Anticancer agent 75			Topoisomerase II
Intoplicine dimesylate		Topoisomerase I	Topoisomerase II	98.28%
Topoisomerase II inhibitor 19			Topoisomerase II, IC₅₀: 0.34 μM
Heliquinomycin		Topoisomerase I	Topoisomerase II
Topoisomerase IIα-IN-7			topoisomerase II alpha, IC₅₀: 7.7 μM
Topoisomerase I inhibitor 2		Topoisomerase I, IC₅₀: 0.58 μM
TP3011		Topoisomerase I
Topoisomerase IIα-IN-3			topoisomerase II alpha
Saintopin		Topoisomerase I	Topoisomerase II
LMP517		Topoisomerase I	Topoisomerase II
Topoisomerase II inhibitor 20			Topoisomerase II, IC₅₀: 0.98 μM
Topoisomerase I/II inhibitor 2		Topoisomerase I	Topoisomerase II
Bimolane			Topoisomerase II
HSP90-IN-13	Topoisomerase-2, IC₅₀: 25.85 nM
CP-67804			Topoisomerase II
Top/HDAC-IN-2		Top1	Topoisomerase II
Topoisomerase IIα-IN-6			topoisomerase II alpha, IC₅₀: 0.67 μM
T-2513		Topoisomerase I
Topoisomerase II inhibitor 18			Topoisomerase II, IC₅₀: 7.5 μM
Topoisomerase IIα-IN-8			topoisomerase II alpha
Topoisomerase IIα-IN-1			topoisomerase II alpha topoisomerase II beta
Topoisomerase II inhibitor 7			topoisomerase II alpha, IC₅₀: 3.19 μM
AQ4			Topoisomerase II
Topo I/COX-2-IN-2		Topoisomerase I, IC₅₀: 0.90 μM
CP-67015			Topoisomerase II
Topoisomerase I inhibitor 8		Topoisomerase I
Topoisomerase II inhibitor 10			Topoisomerase II, IC₅₀: 7.45 μM
9-Hydroxyellipticine hydrochloride			Topoisomerase II
Topoisomerase I inhibitor 16		Topoisomerase I
Pixantrone hydrochloride			Topoisomerase II
EGFR-IN-57			topoisomerase II beta, IC₅₀: 0.13 μM
Topoisomerase II inhibitor 17			Topoisomerase II, IC₅₀: 0.23 μM
Topoisomerase IV inhibitor 2	TOPO IV, IC₅₀: 0.35 μM
Luotonin F			Topoisomerase II
Gatifloxacin mesylate			Topoisomerase II, IC₅₀: 36.7 μM
Voreloxin			Topoisomerase II
Garenoxacin	TOPO IV, IC₅₀: 1.5-2.5 μg/mL
Epirubicin	Topoisomerase
AZD5099			Topoisomerase II
Idarubicin			Topoisomerase II

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。沪(浦)应急管危经许[2021]201709(QFYS)

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Topoisomerase Inhibitors

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