1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. AZD5213

AZD5213 是一种选择性和竞争性的人 H3 受体拮抗剂,对 hH3R 的 pKi 为 9.3。AZD5213 可用于睡眠与认知调节的研究。

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AZD5213 Chemical Structure

AZD5213 Chemical Structure

CAS No. : 1119807-02-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZD5213 is a selective and competitive human H3 receptor antagonist with a pKi value of 9.3 for hH3R. AZD5213 can be used for the research of sleep and cognitive regulation[1][2].

体内研究
(In Vivo)

AZD5213 (1 mg/kg;静脉注射一次) 迅速减少 [11C] 4-(1S,2S)-2-(4-cyclobutylpiperazine-1-carbonyl)-cyclopropyl]-N-methyl-benzamide 与小鼠大脑所有区域的结合[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

327.42

Formula

C19H25N3O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AZD5213
目录号:
HY-129250
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