1. Biology Dictionary
  2. IκB kinase(IKK)

IκB kinase(IKK)IκB 激酶

释义:

IκB kinase (IKK) complex, the master kinase for NF-κB activation, contains two kinase subunits, IKKα and IKKβ. In addition to mediating NF-κB signaling by phosphorylating IκB proteins during inflammatory and immune responses, the activation of the IKK complex also responds to various stimuli to regulate diverse functions independently of NF-κB.

IκB 激酶 (IKK) 复合体是 NF-κB 激活的主激酶,包含两个激酶亚基,IKKα 和 IKKβ。除了在炎症和免疫反应中通过磷酸化 IκB 蛋白介导 NF-κB 信号外,IKK 复合体的激活还对各种刺激作出反应,以调节独立于NF-κB的各种功能。

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