2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK2-IN-18

CDK2-IN-18 (compound 8q) 是 CDK2/E 和 CDK4/D1 的有效抑制剂，IC50 分别为 8 nM 和 46 nM。CDK2-IN-18 抑制肿瘤细胞的增殖。

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CDK2-IN-18 Chemical Structure

CDK2-IN-18 Chemical Structure

CAS No. : 364735-73-9

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CDK2-IN-18 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

查看所有亚型
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDK2-IN-18 (compound 8q) is a potent inhibitor of CDK2/E and CDK4/D1, with IC50s of 8 nM and 46 nM, respectively. CDK2-IN-18 inhibits the proliferation of tumor cells[1].

IC50 & Target

CDK2/cyclinE

8 nM (IC50)

Cdk4/cyclin D1

46 nM (IC50)

分子量

437.52

Formula

C21H23N7O2S
CAS 号
非同位 CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CDK2-IN-18 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK2-IN-18364735-73-9CDKCyclin dependent kinaseHT29 cellsHT1080 cellstumorInhibitorinhibitorinhibit

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产品名称：
CDK2-IN-18
目录号：
HY-155602
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