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  4. Chlorphenesin carbamate

Chlorphenesin carbamate  (Synonyms: 氯苯氨酸甘油酯; Maolate; U 19646)

目录号: HY-107944 纯度: 99.92%
COA 产品使用指南

摩尔计算器

Chlorphenesin carbamate 是一种作用于中枢的骨骼肌松弛剂。Chlorphenesin carbamate 可用于与骨骼肌创伤和炎症相关的疼痛研究。Chlorphenesin carbamate 是脊髓多突触通路的选择性阻断剂。具有镇痛作用。

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Chlorphenesin carbamate Chemical Structure

Chlorphenesin carbamate Chemical Structure

CAS No. : 886-74-8

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Customer Review

Chlorphenesin carbamate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant. Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation[1]. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels[2]. Antinociceptive effect[3].

体内研究
(In Vivo)

Chlorphenesin carbamate (CPC; 50 mg/kg i.v.) inhibits the mono (MSR) and poly-synaptic reflex (PSR), the latter being more susceptible than the former to CPC depression. Chlorphenesin carbamate has an apparent depressant action on the spinal neuron, and it hyperpolarized both the ventral and dorsal roots of the isolated frog spinal cord[2].
Chlorphenesin carbamate (CPC) has an antinociceptive action in adjuvant arthritic rats. Chlorphenesin carbamate (100-400 mg/kg, p.o.) has a dose-dependent antinociceptive effect in the behavioral study. Chlorphenesin carbamate (25-50 mg/kg, i.v.) depresses the evoked neuronal responses of nociceptive neurons in the ventrobasal thalamus (VB) in the electrophysiological study. Chlorphenesin carbamate (50 mg/kg, i.v.) depresses the spontaneous firings of the VB nociceptive neurons[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wister rats weighing 200-300 g[3]
Dosage: 50 mg/kg
Administration: Intravenously administered
Result: Significantly inhibited PSR, with the maximum inhibition at 40 min after the drug administration.
分子量

245.66

Formula

C10H12ClNO4
CAS 号
性状

固体

颜色

White to off-white

中文名称

氯苯氨酸甘油酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 125 mg/mL (508.83 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.0707 mL 20.3533 mL 40.7067 mL
5 mM 0.8141 mL 4.0707 mL 8.1413 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Chlorphenesin carbamate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0707 mL 20.3533 mL 40.7067 mL 101.7667 mL
5 mM 0.8141 mL 4.0707 mL 8.1413 mL 20.3533 mL
10 mM 0.4071 mL 2.0353 mL 4.0707 mL 10.1767 mL
15 mM 0.2714 mL 1.3569 mL 2.7138 mL 6.7844 mL
20 mM 0.2035 mL 1.0177 mL 2.0353 mL 5.0883 mL
25 mM 0.1628 mL 0.8141 mL 1.6283 mL 4.0707 mL
30 mM 0.1357 mL 0.6784 mL 1.3569 mL 3.3922 mL
40 mM 0.1018 mL 0.5088 mL 1.0177 mL 2.5442 mL
50 mM 0.0814 mL 0.4071 mL 0.8141 mL 2.0353 mL
60 mM 0.0678 mL 0.3392 mL 0.6784 mL 1.6961 mL
80 mM 0.0509 mL 0.2544 mL 0.5088 mL 1.2721 mL
100 mM 0.0407 mL 0.2035 mL 0.4071 mL 1.0177 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chlorphenesin carbamate886-74-8Maolate U 19646氯苯氨酸甘油酯U19646U 19646U-19646OthersCentrallyskeletalmusclerelaxantpaintraumainflammationAntinociceptiveInhibitorinhibitorinhibit

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