2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 老药新用化合物库系列
  6. 非专利药物库
非专利药物库 - Off-patent Drug Library

Cat. No.: HY-L141

与新药研发相比，药物重定位（也称为老药新用）具有很多优势,比如药物研发失败风险相对较低，研发周期较短，研发成本相对较少等。但老药新用项目仍然面临一定的风险，包括监管和知识产权问题。由于非专利药物可立即用于临床研究，具有较高的可行性和相对较低的风险，是重新定位的最佳选择。

MCE精心准备了2566种非专利药物，是进行老药新用研究的最佳选择。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 非专利药物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，2493 个产品以 10 mM 浓度提供，50 个产品以 2 mM 浓度提供，23 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 2566 off-patent approved drugs that can be used for high throughput screening (HTS) and high content screening (HCS).

•   Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more.

•   A good choice for drug repurposing.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 2566 off-patent drugs supplied as pre-dissolved Solutions or Solid.
Solution: 2493 compounds supplied in 10 mM solution, 50 compounds supplied in 2 mM solution, 23 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

COX (90)

mAChR (69)

HIV (68)

HSV (27)

nAChR (27)

iGluR (25)

VEGFR (23)

HBV (22)

PPAR (20)

PDGFR (14)

MMP (13)

STAT (13)

PKC (11)

ERK (10)

FGFR (9)

HCV (9)

Akt (8)

AMPK (8)

CMV (8)

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定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Off-patent Drug Library
    目录号：
    HY-L141
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