2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Cytochrome P450
  4. Clobetasol 17-Propionate-d5

Clobetasol 17-Propionate-d5  (Synonyms: 17-丙酸氯倍他索-d5)

目录号: HY-W744187
产品使用指南 技术支持

Clobetasol 17-Propionate-d5 是 Clobetasol propionate (HY-13600) 的氘代物。Clobetasol propionate 是一种有效的，选择性的 CYP3A5 抑制剂，IC50 为 0.206 μM。Clobetasol propionate 不会抑制 CYP3A4 或其他主要 CYP。Clobetasol propionate 是一种皮质类固醇，具有用于研究牛皮癣和其他皮肤病的潜力。

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Clobetasol 17-Propionate-d<sub>5</sub> Chemical Structure

Clobetasol 17-Propionate-d5 Chemical Structure

CAS No. : 2280940-18-1

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Other Forms of Clobetasol 17-Propionate-d5:

Clobetasol 17-Propionate-d5 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

生物活性

Clobetasol 17-Propionate-d5 is the deuterium labeled Clobetasol propionate (HY-13600). Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research[1][2][3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clobetasol 17-Propionate-d5 相关抗体:
分子量

472.00

Formula

C25H27D5ClFO5
CAS 号
非标记 CAS
中文名称

17-丙酸氯倍他索-d5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Clobetasol 17-Propionate-d5 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clobetasol 17-Propionate-d52280940-18-117-丙酸氯倍他索-d5Isotope-Labeled CompoundsCytochrome P450CYPsInhibitorinhibitorinhibit

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