1. GPCR/G Protein Metabolic Enzyme/Protease
  2. G protein-coupled Bile Acid Receptor 1 Endogenous Metabolite
  3. Deoxycholic acid-d4

Deoxycholic acid-d4  (Synonyms: 去氧胆酸 d4)

目录号: HY-N0593S 纯度: ≥98.0%
COA 产品使用指南

Deoxycholic acid-d4 是 Deoxycholic acid 的氘代物。Deoxycholic acid 激活 G 蛋白偶联胆汁酸受体TGR5

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Deoxycholic acid-d<sub>4</sub> Chemical Structure

Deoxycholic acid-d4 Chemical Structure

CAS No. : 112076-61-6

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规格 价格 是否有货 数量
1 mg ¥600
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5 mg ¥2800
In-stock
10 mg ¥4800
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100 mg   询价  

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Deoxycholic acid-d4 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

396.60

Formula

C24H36D4O4

CAS 号
性状

固体

颜色

White to off-white

中文名称

去氧胆酸 d4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (252.14 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.5214 mL 12.6072 mL 25.2143 mL
5 mM 0.5043 mL 2.5214 mL 5.0429 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥98.0%

参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5214 mL 12.6072 mL 25.2143 mL 63.0358 mL
5 mM 0.5043 mL 2.5214 mL 5.0429 mL 12.6072 mL
10 mM 0.2521 mL 1.2607 mL 2.5214 mL 6.3036 mL
15 mM 0.1681 mL 0.8405 mL 1.6810 mL 4.2024 mL
20 mM 0.1261 mL 0.6304 mL 1.2607 mL 3.1518 mL
25 mM 0.1009 mL 0.5043 mL 1.0086 mL 2.5214 mL
30 mM 0.0840 mL 0.4202 mL 0.8405 mL 2.1012 mL
40 mM 0.0630 mL 0.3152 mL 0.6304 mL 1.5759 mL
50 mM 0.0504 mL 0.2521 mL 0.5043 mL 1.2607 mL
60 mM 0.0420 mL 0.2101 mL 0.4202 mL 1.0506 mL
80 mM 0.0315 mL 0.1576 mL 0.3152 mL 0.7879 mL
100 mM 0.0252 mL 0.1261 mL 0.2521 mL 0.6304 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Deoxycholic acid-d4
目录号:
HY-N0593S
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