HER-2 Positive Breast Cancer  (HER-2 阳性乳腺癌)

HER2阳性乳腺癌是一种乳腺癌亚型，其特征是人类表皮生长因子受体2 (HER2) 蛋白过度表达，从而促进癌细胞快速生长。与HER2阴性乳腺癌相比，HER2阳性乳腺癌往往更具侵袭性、生长速度更快，且复发风险更高。约20-30%的乳腺癌为HER2阳性乳腺癌。常见症状包括乳房出现新肿块或增厚、乳头外观改变（例如内陷）以及乳房大小或形状改变。HER2阳性乳腺癌与肿瘤进展和转移风险增加相关，因此靶向治疗对于有效治疗至关重要。

HER2-positive breast cancer is a subtype of breast cancer characterized by overexpression of the human epidermal growth factor receptor 2 (HER2) protein, which promotes rapid cancer cell growth. It tends to be more aggressive, grow faster, and has a higher risk of recurrence compared to HER2-negative breast cancer. Approximately 20-30% of breast cancers are HER2-positive. Common signs include a new lump or thickening in the breast, changes in nipple appearance such as inversion, and alterations in breast size or shape. The disease is associated with increased tumor progression and metastasis potential, making targeted therapies essential for effective treatment.

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