2. Apoptosis
  3. Apoptosis
  4. Drozitumab

Drozitumab  (Synonyms: PRO 95780; rhuMAb-DR 5; Anti-Human DR5 Recombinant Antibody)

目录号: HY-P99286

摩尔计算器

Drozitumab (PRO 95780) 是一种与死亡受体 (death receptor DR5) 结合的人激动性单克隆抗体。Drozitumab 对横纹肌肉瘤具有有效的抗肿瘤活性。

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Drozitumab Chemical Structure

Drozitumab Chemical Structure

CAS No. : 912628-39-8

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规格 是否有货
1 mg
询价
5 mg
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Drozitumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Drozitumab (PRO 95780) is a human agonistic monoclonal antibody which binds the death receptor DR5. Drozitumab has potent antitumor activity against rhabdomyosarcoma[1][2][3].

体外研究
(In Vitro)

Drozitumab selectively eliminates cancer stem cells (CSCs), resulting in tumor growth inhibition and even regression of pancreatic tumors[3].
Drozitumab induces apoptosis in mesenchymal TNBC cell lines but not in cell lines from other breast cancer subtypes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Drozitumab 相关抗体:
Clinical Trial
分子量

143.1 (kDa)

CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Drozitumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Drozitumab912628-39-8PRO 95780 rhuMAb-DR 5 Anti-Human DR5 Recombinant AntibodyPRO95780PRO-95780Apoptosiscancer stem cellsPancreatic cancerInhibitorinhibitorinhibit

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