2. Others Membrane Transporter/Ion Channel Neuronal Signaling Autophagy Immunology/Inflammation GPCR/G Protein
  3. Reference Standards TRP Channel Autophagy COX Prostaglandin Receptor Na+/H+ Exchanger (NHE)
  4. EIPA hydrochloride (Standard)

EIPA hydrochloride (Standard)  (Synonyms: L593754 hydrochloride (Standard); MH 12-43 hydrochloride (Standard); Ethylisopropylamiloride hydrochloride (Standard))

目录号: HY-101840AR 纯度: ≥98%
产品使用指南 技术支持

EIPA (hydrochloride) (Standard)是 EIPA (hydrochloride) 的分析标准品。本产品用于研究及分析应用。EIPA (L593754) hydrochloride 是一种具有口服活性的 TRPP3 通道抑制剂，IC50 为 10.5 μM。EIPA hydrochloride 可通过抑制 Na+/H+-exchanger 3 (NHE3) 来促进自噬 (autophagy)。EIPA hydrochloride 也抑制巨胞饮作用 (macropinocytosis)。EIPA hydrochloride 可用于炎症和癌症的研究，如胃癌、结肠癌、胰腺癌。

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EIPA hydrochloride (Standard) Chemical Structure

EIPA hydrochloride (Standard) Chemical Structure

CAS No. : 1345839-28-2

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生物活性

EIPA (hydrochloride) (Standard) is the analytical standard of EIPA (hydrochloride). This product is intended for research and analytical applications. EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma.

分子量

336.22

Formula

C11H19Cl2N7O
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

EIPA hydrochloride (Standard) 相关分类

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Keywords:

EIPA hydrochloride (Standard)1345839-28-2L593754 hydrochloride (Standard)MH 12-43 hydrochloride (Standard)Ethylisopropylamiloride hydrochloride (Standard)Reference StandardsTRP ChannelAutophagyCOXProstaglandin ReceptorNa+/H+ Exchanger (NHE)Transient receptor potential channelsCyclooxygenaseSodium/hydrogen ExchangerSodium-hydrogen ExchangerCation channelNHE3IECsIBDsIEC-18neuronzinccalciumkainiteMKN28gastric cancercolon carcinomapancreatic carcinomarenal failureddY strain miceInhibitorinhibitorinhibit

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