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  4. Epoxyazadiradione

Epoxyazadiradione 

目录号: HY-N10096 纯度: 99.21%
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Epoxyazadiradione 是一种从印楝 (Azadirachta indica) 果实中提纯的柠檬苦素。Epoxyazadiradione 以可逆的方式非竞争性抑制人类 (huMIF) 和疟原虫 (恶性疟原虫 (PfMIF) 和约氏疟原虫 (PyMIF)) 的互变异构酶活性 (Ki，2.11-5.23 μM)。Epoxyazadiradione 具有抗疟原虫和人类 MIF 诱导的促炎反应的潜力。

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Epoxyazadiradione Chemical Structure

Epoxyazadiradione Chemical Structure

CAS No. : 18385-59-6

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规格 价格 是否有货 数量
1 mg ￥1300
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5 mg ￥2900
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10 mg ￥5200
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Epoxyazadiradione 相关抗体

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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  • 参考文献

生物活性

Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (Ki, 2.11-5.23 μM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human[1].

IC50 & Target

Plasmodium

 

分子量

466.57

Formula

C28H34O6
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Epoxyazadiradione 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Epoxyazadiradione18385-59-6ParasitelimonoidMIFhuMIFparasitesproinflammatoryInhibitorinhibitorinhibit

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