2. Others GPCR/G Protein Neuronal Signaling
  3. Isotope-Labeled Compounds Neurokinin Receptor
  4. Fosaprepitant-d4 dimeglumine

Fosaprepitant-d4 dimeglumine  (Synonyms: 福沙吡坦二甲葡胺-d4; MK-0517-d4; L785298-d4)

目录号: HY-14407AS
产品使用指南

摩尔计算器

Fosaprepitant-d4 (dimeglumine) 是 Fosaprepitant (dimeglumine) 氘代物。Fosaprepitant dimeglumine (MK-0517) 是 Aprepitant (HY-10052) 的前体。Fosaprepitant dimeglumine 是一种神经激肽-1 受体 (neurokinin-1 receptor) 拮抗剂，被开发用于预防化疗引起的恶心呕吐 (CINV)。

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Fosaprepitant-d<sub>4</sub> dimeglumine Chemical Structure

Fosaprepitant-d4 dimeglumine Chemical Structure

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规格 是否有货
1 mg
询价
5 mg
询价

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Other Forms of Fosaprepitant-d4 dimeglumine:

Fosaprepitant-d4 dimeglumine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fosaprepitant-d4 (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV)[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Fosaprepitant-d4 dimeglumine 相关抗体:
分子量

1008.86

Formula

C37H52D4F7N6O16P
中文名称

福沙吡坦二甲葡胺-d4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Fosaprepitant-d4 dimeglumine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fosaprepitant-d4 dimeglumineMK-0517-d4L785298-d4福沙吡坦二甲葡胺-d4Isotope-Labeled CompoundsNeurokinin ReceptorNK receptorTachykinin receptorInhibitorinhibitorinhibit

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