2. Anti-infection Cell Cycle/DNA Damage
  3. CMV DNA/RNA Synthesis
  4. Ganciclovir triphosphate disodium

Ganciclovir triphosphate disodium  (Synonyms: GCV-TP disodium)

目录号: HY-131605B 纯度: 98.65%
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Ganciclovir triphosphate (GCV-TP) disodium 是一种合成的 2'-脱氧鸟苷类似物，具有抑制人类巨细胞病毒 (CMV) 复制的活性。Ganciclovir triphosphate disodium 通过与病毒 DNA 聚合酶结合，干扰病毒 DNA 的合成，从而对 CMV 感染有效。Ganciclovir triphosphate disodium 对来自人类、猴子、鼠类和豚鼠的 CMV 株具有良好的抗病毒效果，半数有效浓度 (IC50) 为 0.01 μM。Ganciclovir triphosphate disodium 在基因导向酶前药抑制中也被应用，用于癌症抑制。

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Ganciclovir triphosphate disodium

Ganciclovir triphosphate disodium Chemical Structure

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规格 价格 是否有货 数量
5.412 mg (100 mM * 100 μL in Water) ￥10625
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Ganciclovir triphosphate disodium 相关抗体

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生物活性

Ganciclovir triphosphate (GCV-TP) disodium is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate disodium is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate disodium has an IC50 of 0.01 μM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate disodium has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition[1].

分子量

541.15

Formula

C9H16N5Na2O13P3
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
纯度 & 产品资料
参考文献

Ganciclovir triphosphate disodium 相关分类

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganciclovir triphosphate disodiumGCV-TP disodiumCMVDNA/RNA SynthesisCytomegaloviruscancerantiviralInhibitorinhibitorinhibit

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