1. Gene
  2. Cxcr6 - C-X-C motif chemokine receptor 6 Gene

Cxcr6 - C-X-C motif chemokine receptor 6 Gene

中文名称:CXC 基序趋化因子受体 6

种属: Rattus norvegicus

基因 ID: 100124593 | 基因类型: protein coding

关于 Cxcr6

Primary_assembly 8: 123,416,325-123,439,526 forward strand.mRatBN7.2:CM026981.1

This gene has 2 transcripts (splice variants), 97 orthologues, 24 paralogues and is associated with 1 phenotype.

功能概要

预测该基因编码的蛋白可启动趋化因子结合活性和趋化因子受体活性。预计参与多个过程,包括钙介导的信号传导;细胞趋化性;和细胞溶质钙离子浓度的正调节。预计是膜的组成部分。预计在质膜外侧活跃。与人 CXCR6(CXC 基序趋化因子受体 6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable chemokine binding activity and Chemokine Receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CXCR6 (C-X-C motif Chemokine Receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Cxcr6 基因产物(1)

mRNA Protein Name
NM_001102587.2 NP_001096057.1 C-X-C chemokine receptor type 6

Cxcr6 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (43 - 309)

7tm_GPCRs

7tm_GPCRs: cd14964 (45 - 69)

7tm_GPCRs

7tm_GPCRs: cd14964 (78 - 99)

7tm_GPCRs

7tm_GPCRs: cd14964 (114 - 136)

7tm_GPCRs

7tm_GPCRs: cd14964 (161 - 177)

7tm_GPCRs

7tm_GPCRs: cd14964 (200 - 223)

7tm_GPCRs

7tm_GPCRs: cd14964 (241 - 263)

7tm_GPCRs

7tm_GPCRs: cd14964 (278 - 303)

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  • 354 a.a.
蛋白主名 其他名称

C-X-C chemokine receptor type 6

chemokine (C-X-C motif) receptor 6

chemokine receptor CXCR6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxcr6 NCBI NCBI:10663