2. Gene
  3. ACTR2 - actin related protein 2 Gene

ACTR2 - actin related protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肌动蛋白相关蛋白 2

种属: Homo sapiens

同用名: ARP2

基因 ID: 10097 | 基因类型: protein coding

关于 ACTR2

Cytogenetic location: 2p14 Genomic coordinates (GRCh38): 2:65,227,831-65,271,253 (from NCBI)

This gene has 4 transcripts (splice variants), 260 orthologues and 26 paralogues. Ubiquitous expression in appendix (RPKM 135.1), lymph node (RPKM 134.7) and 25 other tissues.

功能概要

该基因的具体功能尚未确定；然而，已知它编码的蛋白质是 ARP2/3 复合体的主要成分。该复合物位于细胞表面，通过板状足肌动蛋白组装和突起对细胞形状和运动至关重要。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供，2008 年 7 月]

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ACTR2 基因产物(2)

mRNA Protein Name
NM_001005386.3 NP_001005386.1 actin-related protein 2 isoform a
NM_005722.4 NP_005713.1 actin-related protein 2 isoform b

ACTR2 蛋白结构

Actin

Actin: Actin (5 - 388)

  • 0
  • 100
  • 200
  • 300
  • 394 a.a.
蛋白主名 其他名称

actin-related protein 2

ARP2 actin related protein 2 homolog

ACTR2 抗体

目录号 产品名 应用 反应物种
HY-P82980 Actin Related Protein 2 Antibody (YA2725) WB, ICC/IF Human, Mouse, Rat

关联疾病

疾病名称 别名
Wiskott-Aldrich Syndrome

WAS

Eczema-Thrombocytopenia-Immunodeficiency Syndrome

Immunodeficiency 2

Aldrich Syndrome

Imd2

Wiskott-Aldrich Syndrome 1

Was1

Wiskott Syndrome

Wiskott Aldrich Syndrome

Eczema Thrombocytopenia Immunodeficiency Syndrome

Imd 2
Myopathy, Centronuclear, 2

Myopathy, Centronuclear, Autosomal Recessive

Autosomal Recessive Centronuclear Myopathy

CNM2

Centronuclear Myopathy 2

Ar-Cnm

Myotubular Myopathy, Autosomal Recessive

Autosomal Recessive Myotubular Myopathy

Centronuclear Myopathy Autosomal Recessive

Myopathy, Centronuclear, Type 2
Coronin-1a Deficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00230 ACTR2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21472 Actr2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27990 Actr2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ACTR2 MGD MGI:1913963
Canis familiaris ACTR2 VGNC VGNC:37554
Macaca mulatta ACTR2 VGNC VGNC:103782
Bos taurus ACTR2 VGNC VGNC:25586
Rattus norvegicus ACTR2 RGD RGD:1310826
Felis catus ACTR2 VGNC VGNC:59556
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