2. Gene
  3. Numa1 - nuclear mitotic apparatus protein 1 Gene

Numa1 - nuclear mitotic apparatus protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NuMA; 6720401E04Rik

基因 ID: 101706 | 基因类型: protein coding

关于 Numa1

功能概要

Predicted to enable several functions, including disordered domain specific binding activity; dynein complex binding activity; and microtubule binding activity. Involved in several processes, including establishment of mitotic spindle orientation; positive regulation of BMP signaling pathway; and positive regulation of keratinocyte differentiation. Acts upstream of or within lung epithelial cell differentiation. Located in several cellular components, including lateral cell cortex; mitotic spindle pole; and nuclear matrix. Is expressed in lung epithelium; midbrain ventricular layer; olfactory lobe; pigmented retinal epithelium; and telencephalon ventricular layer. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human NUMA1 (nuclear mitotic apparatus protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Numa1 基因产物(11)

mRNA Protein Name
NM_001403544.1 NP_001390473.1 nuclear mitotic apparatus protein 1 isoform a
NM_001403545.1 NP_001390474.1 nuclear mitotic apparatus protein 1 isoform a
NM_001403546.1 NP_001390475.1 nuclear mitotic apparatus protein 1 isoform a
NM_001403547.1 NP_001390476.1 nuclear mitotic apparatus protein 1 isoform a
NM_001403548.1 NP_001390477.1 nuclear mitotic apparatus protein 1 isoform a
NM_001403549.1 NP_001390478.1 nuclear mitotic apparatus protein 1 isoform a
NM_001403550.1 NP_001390479.1 nuclear mitotic apparatus protein 1 isoform a
NM_001403551.1 NP_001390480.1 nuclear mitotic apparatus protein 1 isoform b
NM_001403552.1 NP_001390481.1 nuclear mitotic apparatus protein 1 isoform c
NM_001403553.1 NP_001390482.1 nuclear mitotic apparatus protein 1 isoform d
NM_133947.4 NP_598708.3 nuclear mitotic apparatus protein 1 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25936915 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in establishment of mitotic spindle orientation IMP
IMP: 通过突变表型推断
26765568 MGI
involved in positive regulation of BMP signaling pathway IMP
IMP: 通过突变表型推断
26765568 MGI
involved in positive regulation of hair follicle development IMP
IMP: 通过突变表型推断
26765568 MGI
involved in positive regulation of keratinocyte differentiation IMP
IMP: 通过突变表型推断
26765568 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell cortex region IDA
IDA: 通过直接分析推断
26765568 MGI
located in lateral cell cortex IMP
IMP: 通过突变表型推断
26766442 MGI
located in mitotic spindle pole IDA
IDA: 通过直接分析推断
26765568 MGI
located in nuclear matrix IDA
IDA: 通过直接分析推断
11092755 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear mitotic apparatus protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09680 NUMA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21675 Numa1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28193 Numa1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Numa1 NCBI NCBI:4926
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