BTN3A3 - butyrophilin subfamily 3 member A3 Gene

中文名称：嗜乳脂蛋白亚家族 3 成员 A3

种属: Homo sapiens

同用名: BTF3; BTN3.3

关于 BTN3A3

功能概要

嗜乳脂蛋白 (BTN) 基因是一组主要组织相容性复合体 (MHC) 相关基因，编码具有 2 个细胞外免疫球蛋白 (Ig) 结构域和细胞内 B30.2 (PRYSPRY) 结构域的 I 型膜蛋白。人类 BTN 基因的三个亚家族位于 MHC I 类区域：单拷贝 BTN1A1 基因 (MIM 601610) 和 BTN2 (例如，BTN2A1；MIM 613590) 和 BTN3 (例如，BNT3A3) 基因，它们经历了串联复制，每份各有 3 份 (Smith 等人总结，2010 [PubMed 20208008]) 。[OMIM 提供，2010 年 11 月]

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]