2. Gene
  3. Kdm3a - lysine (K)-specific demethylase 3A Gene

Kdm3a - lysine (K)-specific demethylase 3A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TGSA; Tsga; Jmjd1; KDM2A; JHDM2a; Jmjd1a; 1700105C21Rik; C230043E16Rik

基因 ID: 104263 | 基因类型: protein coding

关于 Kdm3a

功能概要

Enables chromatin binding activity and transcription coregulator activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; histone modification; and spermatid nucleus elongation. Located in cytoplasm and nucleus. Is expressed in pituitary gland. Used to study obesity. Human ortholog(s) of this gene implicated in cervical Cancer and colon Cancer. Orthologous to human KDM3A (lysine demethylase 3A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm3a 基因产物(4)

mRNA Protein Name
NM_001038695.3 NP_001033784.2 lysine-specific demethylase 3A isoform a
NM_001362200.1 NP_001349129.1 lysine-specific demethylase 3A isoform a
NM_001362201.1 NP_001349130.1 lysine-specific demethylase 3A isoform b
NM_173001.3 NP_766589.1 lysine-specific demethylase 3A isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
17943087 MGI
enables histone H3K9 demethylase activity IDA
IDA: 通过直接分析推断
17991879 MGI
enables histone H3K9 demethylase activity IMP
IMP: 通过突变表型推断
17938240 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17991879 MGI
enables transcription coregulator activity IDA
IDA: 通过直接分析推断
17991879 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
19194461 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17991879 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
17938240 MGI
acts upstream of or within regulation of stem cell differentiation IMP
IMP: 通过突变表型推断
17938240 MGI
acts upstream of or within regulation of stem cell population maintenance IGI
IGI: 通过遗传相互作用推断
17938240 MGI
acts upstream of or within spermatid nucleus elongation IMP
IMP: 通过突变表型推断
17943087 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
17943087 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17943087 MGI
located in male germ cell nucleus IDA
IDA: 通过直接分析推断
17943087 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17599069 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase 3A

[histone H3]-dimethyl-L-lysine(9) demethylase 3A

jmjC domain-containing histone demethylation protein 2A

jumonji domain-containing protein 1A

testis specific gene A

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12304 IOX1 Inhibitor 99.89% 否
HY-168593 PROTAC KDM3 degrader-1 99.07% 否
HY-RS07211 KDM3A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17111 Kdm3a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23556 Kdm3a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm3a NCBI NCBI:55818
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