1. Gene
  2. Ddx1 - DEAD box helicase 1 Gene

Ddx1 - DEAD box helicase 1 Gene

种属: Mus musculus

同用名: DBP-RB

基因 ID: 104721 | 基因类型: protein coding

关于 Ddx1

功能概要

Enables double-stranded RNA binding activity. Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of myeloid dendritic cell cytokine production. Acts upstream of or within response to exogenous dsRNA and response to virus. Located in cytoplasmic stress granule; cytosol; and mitochondrion. Is expressed in several structures, including 1st branchial arch; cardiovascular system; central nervous system; genitourinary system; and stomach. Orthologous to human DDX1 (DEAD-box helicase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddx1 基因产物(1)

mRNA Protein Name
NM_134040.1 NP_598801.1 ATP-dependent RNA helicase DDX1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables double-stranded RNA binding IDA
IDA: 通过直接分析推断
21703541 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18758164 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
21703541 MGI
involved in positive regulation of myeloid dendritic cell cytokine production IMP
IMP: 通过突变表型推断
21703541 MGI
acts upstream of or within response to exogenous dsRNA IMP
IMP: 通过突变表型推断
21703541 MGI
acts upstream of or within response to virus IMP
IMP: 通过突变表型推断
21703541 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
21933836 MGI
located in cytosol IDA
IDA: 通过直接分析推断
21703541 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
21703541 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ATP-dependent RNA helicase DDX1

DEAD (Asp-Glu-Ala-Asp) box polypeptide 1

DEAD box protein 1

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ddx1 NCBI NCBI:1653