2. Gene
  3. Ovol2 - ovo like zinc finger 2 Gene

Ovol2 - ovo like zinc finger 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MOVO; Ovo2; M-OVO; movo2; Zfp339; M-OVO-A; M-OVO-B; 1700108N11Rik; 1810007D21Rik

基因 ID: 107586 | 基因类型: protein coding

关于 Ovol2

功能概要

Enables DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and chromatin binding activity. Involved in several processes, including negative regulation of epithelial to mesenchymal transition; regulation of SMAD protein signal transduction; and regulation of gene expression. Acts upstream of or within several processes, including circulatory system development; embryonic morphogenesis; and regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; gut; head surface ectoderm; and otocyst. Human ortholog(s) of this gene implicated in posterior polymorphous corneal dystrophy 1. Orthologous to human OVOL2 (ovo like zinc finger 2). [provided by Alliance of Genome Resources, Apr 2022]

Ovol2 基因产物(2)

mRNA Protein Name
NM_026924.3 NP_081200.2 transcription factor Ovo-like 2 isoform A
NM_152947.2 NP_694455.2 transcription factor Ovo-like 2 isoform B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
15225875 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
24735878 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
28455959 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
24735878 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
17573777 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
16423343 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: 通过突变表型推断
16423343 MGI
acts upstream of or within embryonic digestive tract morphogenesis IMP
IMP: 通过突变表型推断
16423343 MGI
acts upstream of or within endocardium formation IMP
IMP: 通过突变表型推断
17573777 MGI
involved in epidermal cell differentiation IMP
IMP: 通过突变表型推断
24735879 MGI
acts upstream of or within epidermis development IGI
IGI: 通过遗传相互作用推断
24735878 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
16423343 MGI
acts upstream of or within heart looping IMP
IMP: 通过突变表型推断
17573777 MGI
acts upstream of or within heart trabecula formation IMP
IMP: 通过突变表型推断
17573777 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: 通过突变表型推断
17573777 MGI
involved in negative regulation of SMAD protein signal transduction IDA
IDA: 通过直接分析推断
28455959 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16423343 MGI
involved in negative regulation of epithelial to mesenchymal transition IDA
IDA: 通过直接分析推断
28455959 MGI
involved in negative regulation of epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
24735879 MGI
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
28455959 MGI
acts upstream of or within negative regulation of stem cell proliferation IGI
IGI: 通过遗传相互作用推断
24735878 MGI
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
28455959 MGI
acts upstream of or within neural crest cell migration IMP
IMP: 通过突变表型推断
16423343 MGI
acts upstream of or within neural fold formation IMP
IMP: 通过突变表型推断
16423343 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
28455959 MGI
acts upstream of or within positive regulation of keratinocyte differentiation IDA
IDA: 通过直接分析推断
24735878 MGI
involved in regulation of keratinocyte proliferation IMP
IMP: 通过突变表型推断
19700410 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9468311 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor Ovo-like 2

MOVO-B zinc finger protein

MOVO-C zinc finger protein

OVO homolog-like 2

ovo-like 2

zinc finger OVO2

zinc finger protein 339

zinc finger protein mOVO

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09884 OVOL2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22705 Ovol2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29219 Ovol2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ovol2 NCBI NCBI:58495
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