2. Gene
  3. Atic - 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Gene

Atic - 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 2610509C24Rik

基因 ID: 108147 | 基因类型: protein coding

关于 Atic

功能概要

Enables IMP cyclohydrolase activity and phosphoribosylaminoimidazolecarboxamide formyltransferase activity. Involved in purine ribonucleoside monophosphate biosynthetic process. Acts upstream of or within cellular response to interleukin-7. Located in mitochondrion. Is expressed in several structures, including alimentary system; heart; nervous system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in purine-pyrimidine metabolic disorder. Orthologous to human ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase). [provided by Alliance of Genome Resources, Apr 2022]

Atic 基因产物(1)

mRNA Protein Name
NM_026195.3 NP_080471.2 bifunctional purine biosynthesis protein ATIC
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables IMP cyclohydrolase activity IMP
IMP: 通过突变表型推断
6480832 MGI
enables phosphoribosylaminoimidazolecarboxamide formyltransferase activity IMP
IMP: 通过突变表型推断
26144885 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 'de novo' AMP biosynthetic process IMP
IMP: 通过突变表型推断
26144885 MGI
involved in 'de novo' IMP biosynthetic process IMP
IMP: 通过突变表型推断
26144885 MGI
involved in 'de novo' XMP biosynthetic process IMP
IMP: 通过突变表型推断
26144885 MGI
involved in GMP biosynthetic process IMP
IMP: 通过突变表型推断
26144885 MGI
acts upstream of or within cellular response to interleukin-7 IDA
IDA: 通过直接分析推断
29581031 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bifunctional purine biosynthesis protein ATIC

AICAR transformylase/inosine monophosphate cyclohydrolase

bifunctional purine biosynthesis protein PURH

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-N0485 Liensinine Diperchlorate Inhibitor 99.96% Phase 2
HY-135238 (rel)-RSD 921 Agonist / Phase 2
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990067 Evunzekibart Inhibitor 97.02% Phase 1
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150252A ATIC-IN-1 acetate Inhibitor 99.96% 否
HY-N1448 Vincetoxicoside B Inhibitor 99.70% 否
HY-29244 ATIC-IN-2 Inhibitor ≥98.0% 否
HY-133157 FAICAR 85.00% 否
HY-150252 ATIC-IN-1 99.69% 否
HY-E70121 Succinyl-CoA synthetase / 否
HY-141324 Tetraethyl butane-​1,​4-​diylbis(phosphoramid​ate) / 否
HY-RS01126 ATE1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01156 ATIC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17124 Atic Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23569 Atic Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atic NCBI NCBI:471
Canis lupus familiaris Atic NCBI
Rattus norvegicus Atic NCBI NCBI:81643
Macaca mulatta Atic NCBI NCBI:694819
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