1. Gene
  2. CEACAM7 - CEA cell adhesion molecule 7 Gene

CEACAM7 - CEA cell adhesion molecule 7 Gene

中文名称:CEA 细胞粘附分子 7

种属: Homo sapiens

同用名: CGM2

基因 ID: 1087 | 基因类型: protein coding

关于 CEACAM7

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,673,303-41,688,270 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 569 orthologues and 24 paralogues. Restricted expression toward colon (RPKM 448.6).

功能概要

该基因编码细胞表面糖蛋白和癌胚抗原 (CEA) 蛋白家族的成员。该基因的表达可能在结肠癌和直肠癌中下调。此外,该基因的较低表达水平可能预示着直肠癌复发。该基因存在于 19 号染色体上的 CEA 家族基因簇中。可变剪接导致多个转录本变体。[RefSeq 提供,2015 年 7 月]

This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal Cancer. Additionally, lower expression levels of this gene may be predictive of rectal Cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

CEACAM7 基因产物(2)

mRNA Protein Name
NM_001291485.2 NP_001278414.1 carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein
NM_006890.5 NP_008821.2 carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein

CEACAM7 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (42 - 141)

Ig_2

Ig_2: Immunoglobulin domain (147 - 234)

  • 0
  • 100
  • 200
  • 265 a.a.
蛋白主名 其他名称

carcinoembryonic antigen-related cell adhesion molecule 7

carcinoembryonic antigen CGM2

重组 CEACAM7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7825 CEACAM7 Protein, Human (HEK293, His) AAI21133.1 (T36-F142) ≥95%
HY-P72132 CEACAM7 Protein, Human (His-SUMO) Q14002 (T36-S242) ≥95%

关联疾病

疾病名称 别名
Mucinous Cystadenocarcinoma

Cystadenocarcinoma, Mucinous

Pseudomucinous Cystadenocarcinoma

Cystadenocarcinoma Mucinous

Gastrointestinal Carcinoma

Gastrointestinal Neoplasms

Adenosquamous Carcinoma

Adenosquamous Cell Carcinoma

Mixed Adenocarcinoma And Squamous Carcinoma

Carcinoma Adenosquamous

Carcinoma, Adenosquamous

Cervical Adenocarcinoma

Adenocarcinoma Cervix Uteri

Adenocarcinoma Of Cervix

Adenocarcinoma Of The Uterine Cervix

Adenocarcinoma Of The Cervix Uteri

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Goblet Cell Carcinoid

Gcc

Goblet Cell Adenocarcinoid

Goblet Cell Carcinoma

Goblet Cell Tumor

Mucinous Carcinoid

Carcinoid Goblet Cell

Carcinoid, Goblet Cell

Rectum Cancer

Malignant Neoplasm Of Rectum

Rectal Cancer

Cancer Of Rectum

Carcinoma Of Rectum

Carcinoma Of The Rectum

Malignant Rectal Tumor

Malignant Rectum Tumor

Malignant Tumor Of Rectum

Rectal Carcinoma

Rectal Cancers

Cancer, Rectal

Ovarian Cyst

Ovarian Cysts

Paget Disease, Extramammary

Extramammary Paget Disease

Cutaneous Paget'S Disease

Extramammary Paget'S Disease

Paget Disease Extramammary

Cutaneous Paget Disease

Paget'S Disease Of Skin

Empd

Extramammary Pagets Disease

Pleural Tuberculosis

Pearly Disease

Tuberculosis Of Pleura

Tuberculous Pleurisy

Tuberculous Pleurisy In Primary Progressive Tuberculosis

Tuberculous Pleuritis

Pleurisy Tuberculous

Tuberculosis, Pleural

Serosal Tuberculosis Of Cattle

Colon Adenocarcinoma

Adenocarcinoma Of Colon

Adenocarcinoma Of The Colon

Colonic Adenocarcinoma

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach

Lung Cancer Susceptibility 3

Lung Adenocarcinoma

Adenocarcinoma Of Lung

LNCR3

Adenocarcinoma Of Lung, Susceptibility To

Bronchogenic Lung Adenocarcinoma

Nonsmall Cell Adenocarcinoma

Adenocarcinoma Lung

Lung Adenocarcinomas

Non-Small Cell Adenocarcinoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CEACAM7 VGNC VGNC:109596
Others CEACAM7 NCBI