2. Gene
  3. Gusb - glucuronidase, beta Gene

Gusb - glucuronidase, beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: g; Gur; Gus; Gut; asd; Gus-r; Gus-s; Gus-t; Gus-u

基因 ID: 110006 | 基因类型: protein coding

关于 Gusb

功能概要

Enables beta-glucuronidase activity. Acts upstream of or within glucuronoside catabolic process. Located in extracellular space and lysosome. Is expressed in several structures, including alimentary system; brain; heart; sensory organ; and viscerocranium. Used to study Sly syndrome. Human ortholog(s) of this gene implicated in Sly syndrome. Orthologous to human GUSB (glucuronidase beta). [provided by Alliance of Genome Resources, Apr 2022]

Gusb 基因产物(4)

mRNA Protein Name
NM_001357025.1 NP_001343954.1 beta-glucuronidase isoform 2
NM_001357026.1 NP_001343955.1 beta-glucuronidase isoform 3 precursor
NM_001357027.1 NP_001343956.1 beta-glucuronidase isoform 4 precursor
NM_010368.2 NP_034498.1 beta-glucuronidase isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-glucuronidase activity IDA
IDA: 通过直接分析推断
1914521 MGI
enables beta-glucuronidase activity IMP
IMP: 通过突变表型推断
9774663 MGI
enables hydrolase activity IDA
IDA: 通过直接分析推断
19710420 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within carbohydrate metabolic process IDA
IDA: 通过直接分析推断
4841576 MGI
involved in chondroitin sulfate catabolic process IMP
IMP: 通过突变表型推断
23897660 MGI
involved in heparan sulfate proteoglycan catabolic process IMP
IMP: 通过突变表型推断
11273777 MGI
involved in hyaluronan catabolic process IMP
IMP: 通过突变表型推断
20385825 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19710420 MGI
is active in lysosomal lumen IDA
IDA: 通过直接分析推断
8200966 MGI
is active in lysosomal lumen IMP
IMP: 通过突变表型推断
23897660 MGI
is active in lysosome IDA
IDA: 通过直接分析推断
4841576 MGI
located in lysosome IDA
IDA: 通过直接分析推断
4841576 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

beta-glucuronidase

adipose storage deficiency

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05927 GUSB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20750 Gusb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27262 Gusb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gusb NCBI NCBI:2990
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