2. Gene
  3. Chrna5 - cholinergic receptor, nicotinic, alpha polypeptide 5 Gene

Chrna5 - cholinergic receptor, nicotinic, alpha polypeptide 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Acra5; Acra-5

基因 ID: 110835 | 基因类型: protein coding

关于 Chrna5

功能概要

Predicted to enable acetylcholine binding activity and acetylcholine-gated cation-selective channel activity. Predicted to contribute to acetylcholine receptor activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within response to nicotine. Located in dopaminergic synapse. Part of acetylcholine-gated channel complex. Is expressed in gut; lung; nervous system; and thymus. Human ortholog(s) of this gene implicated in lung Cancer. Orthologous to human CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna5 基因产物(3)

mRNA Protein Name
NM_001373901.1 NP_001360830.1 neuronal acetylcholine receptor subunit alpha-5 isoform 1 precursor
NM_001373902.1 NP_001360831.1 neuronal acetylcholine receptor subunit alpha-5 isoform 3 precursor
NM_176844.5 NP_789814.2 neuronal acetylcholine receptor subunit alpha-5 isoform 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
19693710 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
19693710 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IDA
IDA: 通过直接分析推断
32817066 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IMP
IMP: 通过突变表型推断
32817066 MGI
acts upstream of or within response to nicotine IMP
IMP: 通过突变表型推断
9495872 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of acetylcholine-gated channel complex IPI
IPI: 通过物理相互作用推断
17434683 MGI
is active in cholinergic synapse IDA
IDA: 通过直接分析推断
32817066 MGI
is active in cholinergic synapse IMP
IMP: 通过突变表型推断
32817066 MGI
is active in dopaminergic synapse IDA
IDA: 通过直接分析推断
19693710 MGI
is active in dopaminergic synapse IMP
IMP: 通过突变表型推断
19693710 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuronal acetylcholine receptor subunit alpha-5

nicotinic acetylcholine receptor alpha5 subunit

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS19054 Chrna5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS02670 CHRNA5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25544 Chrna5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrna5 NCBI NCBI:1138
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