2. Gene
  3. Egr2 - early growth response 2 Gene

Egr2 - early growth response 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Krox20

基因 ID: 114090 | 基因类型: protein coding

关于 Egr2

功能概要

Enables HMG box domain binding activity. Involved in learning or memory; regulation of neuronal synaptic plasticity; and response to Insulin. Predicted to be located in cytoplasm and nucleoplasm. Biomarker of middle cerebral artery infarction. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2). [provided by Alliance of Genome Resources, Apr 2022]

Egr2 基因产物(1)

mRNA Protein Name
NM_053633.2 NP_446085.1 E3 SUMO-protein ligase EGR2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables HMG box domain binding IPI
IPI: 通过物理相互作用推断
16582099 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in learning or memory IEP
IEP: 通过表达模式推断
8619872 RGD
involved in regulation of neuronal synaptic plasticity IEP
IEP: 通过表达模式推断
8619872 RGD
involved in response to insulin IMP
IMP: 通过突变表型推断
12970165 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 SUMO-protein ligase EGR2

E3 SUMO-protein transferase ERG2

EGR-2

early growth response protein 2

zinc finger protein Krox-20

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04216 EGR2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19327 Egr2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25818 Egr2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Egr2 NCBI NCBI:1959
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