1. Gene
  2. Adam2 - a disintegrin and metallopeptidase domain 2 Gene

Adam2 - a disintegrin and metallopeptidase domain 2 Gene

种属: Mus musculus

同用名: Ftnb; Ph30-beta

基因 ID: 11495 | 基因类型: protein coding

关于 Adam2

功能概要

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is predominantly expressed in the epididymis, where the encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Male mice lacking the encoded protein are infertile and exhibit multiple defects in reproduction. [provided by RefSeq, May 2016]

Adam2 基因产物(1)

mRNA Protein Name
NM_009618.3 NP_033748.2 disintegrin and metalloproteinase domain-containing protein 2 preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15194697 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult behavior IMP
IMP: 通过突变表型推断
16504143 MGI
acts upstream of or within cell adhesion IGI
IGI: 通过遗传相互作用推断
21060781 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
16407499 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
19129510 MGI
acts upstream of or within visual learning IMP
IMP: 通过突变表型推断
16504143 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cell surface IDA
IDA: 通过直接分析推断
16407499 MGI
located in cell surface IDA
IDA: 通过直接分析推断
21273369 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
19129510 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

disintegrin and metalloproteinase domain-containing protein 2

a disintegrin and metalloprotease domain 2 (fertilin beta)

fertilin subunit beta

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adam2 NCBI NCBI:2515