TRIM6 - tripartite motif containing 6 Gene

中文名称：含三联基序 6

种属: Homo sapiens

同用名: RNF89

关于 TRIM6

功能概要

由该基因编码的蛋白质是三联基序 (TRIM) 家族的成员。 TRIM 基序包括三个锌结合域、一个 RING、B-box 1 型和 B-box 2 型域，以及一个卷曲螺旋区域。该蛋白质定位于细胞核，但其具体功能尚未确定。该基因被映射到染色体 11p15，位于 TRIM 基因簇内。可变剪接导致多个转录本变体。还观察到从该基因到下游 TRIM34 基因的通读转录本，这导致这些邻近家族成员的融合产物。[RefSeq 提供，2010 年 10 月]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]