1. Gene
  2. Aprt - adenine phosphoribosyl transferase Gene

Aprt - adenine phosphoribosyl transferase Gene

种属: Mus musculus

基因 ID: 11821 | 基因类型: protein coding

关于 Aprt

功能概要

Enables adenine binding activity and adenine phosphoribosyltransferase activity. Involved in AMP salvage; GMP salvage; and IMP salvage. Acts upstream of or within adenine metabolic process; grooming behavior; and purine ribonucleoside salvage. Located in cytosol. Is expressed in several structures, including alimentary system; brain; cranium; genitourinary system; and sensory organ. Used to study adenine phosphoribosyltransferase deficiency. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Orthologous to human APRT (adenine phosphoribosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Aprt 基因产物(1)

mRNA Protein Name
NM_009698.2 NP_033828.2 adenine phosphoribosyltransferase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables adenine binding IDA
IDA: 通过直接分析推断
9218001 MGI
enables adenine phosphoribosyltransferase activity IDA
IDA: 通过直接分析推断
198184 MGI
enables adenine phosphoribosyltransferase activity IGI
IGI: 通过遗传相互作用推断
8485579 MGI
enables adenine phosphoribosyltransferase activity IMP
IMP: 通过突变表型推断
8485579 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in AMP salvage IDA
IDA: 通过直接分析推断
718989 MGI
acts upstream of or within AMP salvage IMP
IMP: 通过突变表型推断
8864750 MGI
involved in AMP salvage IMP
IMP: 通过突变表型推断
8864750 MGI
involved in GMP salvage IDA
IDA: 通过直接分析推断
718989 MGI
involved in IMP salvage IMP
IMP: 通过突变表型推断
9776749 MGI
acts upstream of or within adenine metabolic process IGI
IGI: 通过遗传相互作用推断
8894695 MGI
acts upstream of or within adenine metabolic process IMP
IMP: 通过突变表型推断
8643571 MGI
NOT acts upstream of or within grooming behavior IGI
IGI: 通过遗传相互作用推断
8894695 MGI
acts upstream of or within grooming behavior IGI
IGI: 通过遗传相互作用推断
8485579 MGI
acts upstream of or within purine ribonucleoside salvage IGI
IGI: 通过遗传相互作用推断
8485579 MGI
acts upstream of or within purine ribonucleoside salvage IMP
IMP: 通过突变表型推断
8485579 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
718989 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

adenine phosphoribosyltransferase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aprt NCBI NCBI:353