2. Gene
  3. Cdh11 - cadherin 11 Gene

Cdh11 - cadherin 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cad11; OSF-4

基因 ID: 12552 | 基因类型: protein coding

关于 Cdh11

功能概要

This gene encodes a type II classical Cadherin and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is an integral membrane protein that mediates calcium-dependent cell-cell adhesion, specifically in the context of bone development. Homozygous knockout mice for this gene exhibit impaired synovium development and reduced bone density. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]

Cdh11 基因产物(1)

mRNA Protein Name
NM_009866.5 NP_033996.4 cadherin-11 preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within corticospinal tract morphogenesis IGI
IGI: 通过遗传相互作用推断
22284184 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
10860580 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
10860580 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
10860580 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
10860580 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
12139922 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
10860580 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12139922 MGI
is active in synapse IDA
IDA: 通过直接分析推断
10860580 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cadherin-11

OB-cadherin

osteoblast cadherin

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-177575 CDH11-IN-1 Inhibitor / 否
HY-RS02322 CDH11 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19993 Cdh11 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26497 Cdh11 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdh11 NCBI NCBI:1009
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