2. Gene
  3. Cdh4 - cadherin 4 Gene

Cdh4 - cadherin 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rcad; R-CAD; R-Cadh

基因 ID: 12561 | 基因类型: protein coding

关于 Cdh4

功能概要

This gene encodes a member of the Cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. The encoded protein is involved in retinal angiogenesis during development where it plays a crucial role in the endothelial-astrocyte interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]

Cdh4 基因产物(2)

mRNA Protein Name
NM_001316723.1 NP_001303652.1 cadherin-4 isoform 2 precursor
NM_009867.3 NP_033997.1 cadherin-4 isoform 1 preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of axon extension IDA
IDA: 通过直接分析推断
14586016 MGI
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
14586016 MGI
acts upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
8270638 MGI
acts upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
8270638 MGI
acts upstream of or within positive regulation of axon extension IDA
IDA: 通过直接分析推断
14586016 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
8270638 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cadherin-4

R-cadherin

retina cadherin

retinal cadherin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02337 CDH4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS18750 Cdh4 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS25237 Cdh4 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdh4 NCBI NCBI:1002
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