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  3. Cyba - cytochrome b-245, alpha polypeptide Gene

Cyba - cytochrome b-245, alpha polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: b558; nmf333; p22phox; p22-phox

基因 ID: 13057 | 基因类型: protein coding

关于 Cyba

功能概要

Predicted to enable SH3 domain binding activity; electron transfer activity; and protein heterodimerization activity. Predicted to contribute to superoxide-generating NAD(P)H oxidase activity. Involved in innate immune response. Acts upstream of or within positive regulation of mucus secretion; Reactive Oxygen Species metabolic process; and regulation of release of sequestered calcium ion into cytosol. Located in endosome. Part of NADPH Oxidase complex. Is expressed in several structures, including genitourinary system; hemolymphoid system; inner ear; limb; and liver. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma; chronic obstructive pulmonary disease; and phagocyte bactericidal dysfunction (multiple). Orthologous to human CYBA (cytochrome b-245 alpha chain). [provided by Alliance of Genome Resources, Apr 2022]

Cyba 基因产物(2)

mRNA Protein Name
NM_001301284.1 NP_001288213.1 cytochrome b-245 light chain isoform 2
NM_007806.3 NP_031832.2 cytochrome b-245 light chain isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19755709 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of establishment of localization in cell IMP
IMP: 通过突变表型推断
24185898 MGI
involved in innate immune response IMP
IMP: 通过突变表型推断
28351984 MGI
acts upstream of mucus secretion IMP
IMP: 通过突变表型推断
24185898 MGI
acts upstream of or within positive regulation of mucus secretion IMP
IMP: 通过突变表型推断
24185898 MGI
acts upstream of or within reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
24185898 MGI
acts upstream of or within regulation of release of sequestered calcium ion into cytosol IMP
IMP: 通过突变表型推断
24185898 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of NADPH oxidase complex IDA
IDA: 通过直接分析推断
24739962 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
15850784 MGI
located in endosome IDA
IDA: 通过直接分析推断
24185898 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytochrome b-245 light chain

cytochrome b(558) alpha chain

cytochrome b558 subunit alpha

cytochrome beta-558

neutrophil cytochrome b 22 kDa polypeptide

p22 phagocyte B-cytochrome

p22 phox

superoxide-generating NADPH oxidase light chain subunit

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-176347S Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2 / 否
HY-RS03422 CYBA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19890 Cyba Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26390 Cyba Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyba NCBI NCBI:1535
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