Cyp1a1 - cytochrome P450, family 1, subfamily a, polypeptide 1 Gene

种属: Mus musculus

同用名: AHH; AHRR; CP11; CYPIA1; P450-1

关于 Cyp1a1

功能概要

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Acts upstream of or within several processes, including hydrogen peroxide biosynthetic process; response to toxic substance; and toxin metabolic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including genitourinary system; liver; maxillary process; spleen; and upper jaw. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); diabetes mellitus (multiple); gastrointestinal system Cancer (multiple); hematologic Cancer (multiple); and lung disease (multiple). Orthologous to human CYP1A1 (Cytochrome P450 family 1 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]