1. Gene
  2. Ddc - dopa decarboxylase Gene

Ddc - dopa decarboxylase Gene

种属: Mus musculus

同用名: Aadc

基因 ID: 13195 | 基因类型: protein coding

关于 Ddc

功能概要

Enables aromatic-L-amino-acid decarboxylase activity. Acts upstream of or within response to toxic substance. Located in cytoplasm. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and sensory organ. Used to study aromatic L-amino acid decarboxylase deficiency. Human ortholog(s) of this gene implicated in Parkinson's disease; aromatic L-amino acid decarboxylase deficiency; bipolar disorder; and inherited metabolic disorder. Orthologous to human DDC (dopa decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Ddc 基因产物(2)

mRNA Protein Name
NM_001190448.1 NP_001177377.1 aromatic-L-amino-acid decarboxylase
NM_016672.4 NP_057881.1 aromatic-L-amino-acid decarboxylase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aromatic-L-amino-acid decarboxylase activity IDA
IDA: 通过直接分析推断
23863468 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
22169008 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
22688335 MGI
acts upstream of or within response to toxic substance IDA
IDA: 通过直接分析推断
7904615 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
23010799 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

aromatic-L-amino-acid decarboxylase

重组 Ddc 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74204 DDC Protein, Mouse (sf9, His) O88533 (M1-E480) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ddc NCBI NCBI:1644
Canis familiaris Ddc NCBI NCBI:606852
Macaca fascicularis Ddc NCBI NCBI:102119567