2. Gene
  3. Dld - dihydrolipoamide dehydrogenase Gene

Dld - dihydrolipoamide dehydrogenase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 13382 | 基因类型: protein coding

关于 Dld

功能概要

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. [provided by RefSeq, Jan 2014]

Dld 基因产物(1)

mRNA Protein Name
NM_007861.5 NP_031887.2 dihydrolipoyl dehydrogenase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dihydrolipoyl dehydrogenase activity IMP
IMP: 通过突变表型推断
9405644 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
29128334 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acetyl-CoA biosynthetic process from pyruvate IMP
IMP: 通过突变表型推断
17314311 MGI
acts upstream of or within gastrulation IMP
IMP: 通过突变表型推断
9405644 MGI
acts upstream of or within mitochondrial electron transport, NADH to ubiquinone IMP
IMP: 通过突变表型推断
15009635 MGI
acts upstream of or within proteolysis IDA
IDA: 通过直接分析推断
17404228 MGI
acts upstream of or within regulation of membrane potential IMP
IMP: 通过突变表型推断
15009635 MGI
acts upstream of or within sperm capacitation IDA
IDA: 通过直接分析推断
15888450 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of acetyltransferase complex IMP
IMP: 通过突变表型推断
9405644 MGI
located in acrosomal matrix IDA
IDA: 通过直接分析推断
15888450 MGI
located in cilium IDA
IDA: 通过直接分析推断
15888450 MGI
is active in mitochondrial matrix IDA
IDA: 通过直接分析推断
9405644 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
15888450 MGI
part of oxoglutarate dehydrogenase complex IMP
IMP: 通过突变表型推断
15356189 MGI
part of pyruvate dehydrogenase complex IMP
IMP: 通过突变表型推断
9405644 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dihydrolipoyl dehydrogenase, mitochondrial

branched chain alpha-keto acid dehydrogenase complex subunit E3

相关产品

Pre-clinical Phase
生物活性分子 (22)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122312 BAY-8002 Inhibitor 98.39% 否
HY-119257 ABT-100 98.18% 否
HY-139691 SR15006 Inhibitor 99.95% 否
HY-156375 PKM2 activator 6 / 否
HY-169652 NPC26 Activator ≥98.0% 否
HY-120667 DS-5272 / 否
HY-118829 3,4-Methylenedioxy PV9 hydrochloride 99.90% 否
HY-161654 PROTAC SOS1 degrader-10 / 否
HY-163816 Antiproliferative agent-53-d3 Inhibitor / 否
HY-165606 SB-T-1214 Inducer / 否
HY-168716 SOS1-IN-17 Inhibitor / 否
HY-168733 LDHA-IN-9 / 否
HY-176701 PRMT5-MTA-IN-4 Inhibitor / 否
HY-RS03794 DLD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04711 FAM3A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07574 LDHD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-121619 Jacaric acid Inducer / 否
HY-122063 FR260330 Inhibitor / 否
HY-N13886 Anicequol / 否
HY-N7305 Jatrophane 5 Inhibitor / 否
HY-RS19107 Dld Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25597 Dld Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dld NCBI NCBI:1738
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