Dst - dystonin Gene

种属: Mus musculus

同用名: ah; dt; Bpag; BP230; Bpag1; Macf2; nmf203; nmf339; BPAG1-n; athetoid; mKIAA0728; 2310001O04Rik; A830042E19Rik

关于 Dst

功能概要

Enables microtubule binding activity and protein homodimerization activity. Involved in Cytoskeleton organization and intracellular transport. Acts upstream of or within several processes, including cytoplasmic microtubule organization; regulation of microtubule polymerization or depolymerization; and retrograde axonal transport. Located in several cellular components, including cytoskeleton; endoplasmic reticulum; and sarcomere. Is active in type III intermediate filament. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and retina nuclear layer. Used to study hereditary sensory and autonomic neuropathy type 6 and hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 6. Orthologous to human DST (dystonin). [provided by Alliance of Genome Resources, Apr 2022]