2. Gene
  3. Eif4ebp2 - eukaryotic translation initiation factor 4E binding protein 2 Gene

Eif4ebp2 - eukaryotic translation initiation factor 4E binding protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 4E-BP2; PHAS-II; 2810011I19Rik

基因 ID: 13688 | 基因类型: protein coding

关于 Eif4ebp2

功能概要

Enables eukaryotic initiation factor 4E binding activity and translation repressor activity. Involved in several processes, including memory; negative regulation of translational initiation; and social behavior. Acts upstream of or within TOR signaling and Insulin Receptor signaling pathway. Predicted to be active in cytoplasm. Is expressed in heart; liver; and lung. Used to study autism spectrum disorder. Orthologous to human EIF4EBP2 (eukaryotic translation initiation factor 4E binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Eif4ebp2 基因产物(1)

mRNA Protein Name
NM_010124.2 NP_034254.1 eukaryotic translation initiation factor 4E-binding protein 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables eukaryotic initiation factor 4E binding IMP
IMP: 通过突变表型推断
20347422 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8939971 MGI
enables translation repressor activity IMP
IMP: 通过突变表型推断
16237163 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within TOR signaling IDA
IDA: 通过直接分析推断
8939971 MGI
involved in TOR signaling IMP
IMP: 通过突变表型推断
20347422 MGI
acts upstream of or within insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
8939971 MGI
involved in memory IMP
IMP: 通过突变表型推断
16237163 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
20347422 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
23172145 MGI
involved in negative regulation of translational initiation IMP
IMP: 通过突变表型推断
16237163 MGI
involved in regulation of synaptic plasticity IMP
IMP: 通过突变表型推断
16237163 MGI
involved in social behavior IMP
IMP: 通过突变表型推断
17029989 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

eukaryotic translation initiation factor 4E-binding protein 2

eIF4E-binding protein 2

phosphorylated heat- and acid-stable protein regulated by insulin 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04278 EIF4EBP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20664 Eif4ebp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27175 Eif4ebp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eif4ebp2 NCBI NCBI:1979
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