2. Gene
  3. CRIP1 - cysteine rich protein 1 Gene

CRIP1 - cysteine rich protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富半胱氨酸的蛋白质 1

种属: Homo sapiens

同用名: CRHP; CRIP; CRP1; CRP-1

基因 ID: 1396 | 基因类型: protein coding

关于 CRIP1

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:105,486,886-105,488,947 (from NCBI)

This gene has 6 transcripts (splice variants), 124 orthologues and 20 paralogues. Broad expression in small intestine (RPKM 154.6), lung (RPKM 120.1) and 20 other tissues.

功能概要

富含半胱氨酸肠蛋白 (CRIP) 属于 LIM/双锌指蛋白家族，成员包括富含半胱氨酸和甘氨酸的蛋白-1 (CSRP1; MIM 123876) 、rhombotin-1 (RBTN1; MIM 186921) 、rhombotin -2 (RBTN2；MIM 180385) 和 rhombotin-3 (RBTN3；MIM 180386) 。 CRIP 可能参与肠道锌转运 (Hempe 和 Cousins，1991 [PubMed 1946385]) 。[OMIM 提供，2008 年 3 月]

Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double Zinc Finger Protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]

CRIP1 基因产物(1)

mRNA Protein Name
NM_001311.5 NP_001302.1 cysteine-rich protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptide binding IDA
IDA: 通过直接分析推断
18670594 GOA
enables zinc ion binding IDA
IDA: 通过直接分析推断
9126610 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to UV-B IDA
IDA: 通过直接分析推断
20415737 GOA
involved in cellular response to antibiotic IDA
IDA: 通过直接分析推断
20415737 GOA
involved in immune response IEP
IEP: 通过表达模式推断
20415737 GOA
involved in intrinsic apoptotic signaling pathway in response to DNA damage IDA
IDA: 通过直接分析推断
20415737 GOA
involved in prostate gland stromal morphogenesis IEP
IEP: 通过表达模式推断
9507743 GOA
involved in regulation of gene expression IEP
IEP: 通过表达模式推断
7999070 GOA
involved in response to zinc ion IDA
IDA: 通过直接分析推断
7999070 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
9126610 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CRIP1 蛋白结构

LIM

LIM: LIM domain (4 - 60)

  • 0
  • 77 a.a.
蛋白主名 其他名称

cysteine-rich protein 1

cysteine-rich heart protein

关联疾病

疾病名称 别名
Situs Inversus

Situs Inversus Viscerum

Laterality Sequence

Complete Transposition

Siv
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03175 CRIP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS02920 CNRIP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19671 Crip1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26164 Crip1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus CRIP1 MGD MGI:88501
Canis familiaris CRIP1 VGNC VGNC:50444
Rattus norvegicus CRIP1 RGD RGD:1597237
Felis catus CRIP1 VGNC VGNC:104381
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