2. Gene
  3. Bcl11a - B cell CLL/lymphoma 11A (zinc finger protein) Gene

Bcl11a - B cell CLL/lymphoma 11A (zinc finger protein) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Evi9; Ctip1; Evi9a; Evi9b; Evi9c; BCL-11A; mKIAA1809; 2810047E18Rik; D930021L15Rik

基因 ID: 14025 | 基因类型: protein coding

关于 Bcl11a

功能概要

Enables transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II and protein sumoylation. Acts upstream of or within B cell differentiation; T cell differentiation; and negative regulation of gene expression. Located in nuclear body. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BAF chromatin remodeling complex subunit BCL11A). [provided by Alliance of Genome Resources, Apr 2022]

Bcl11a 基因产物(4)

mRNA Protein Name
NM_001159289.1 NP_001152761.1 B-cell lymphoma/leukemia 11A isoform 2
NM_001159290.1 NP_001152762.1 B-cell lymphoma/leukemia 11A isoform 3
NM_001242934.1 NP_001229863.1 B-cell lymphoma/leukemia 11A isoform 4
NM_016707.3 NP_057916.1 B-cell lymphoma/leukemia 11A isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18681895 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
10744719 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell differentiation IMP
IMP: 通过突变表型推断
12717432 MGI
acts upstream of or within T cell differentiation IMP
IMP: 通过突变表型推断
12717432 MGI
acts upstream of gene expression IMP
IMP: 通过突变表型推断
19657335 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: 通过突变表型推断
19657335 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
29606353 MGI
involved in protein sumoylation IMP
IMP: 通过突变表型推断
18681895 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SWI/SNF complex IDA
IDA: 通过直接分析推断
23644491 MGI
located in nuclear body IDA
IDA: 通过直接分析推断
18681895 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10744719 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

B-cell lymphoma/leukemia 11A

B-cell CLL/lymphoma 11A

COUP-TF interacting protein 1

EVI-9

ecotropic viral integration site 9 protein

myeloid leukemia

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-152775 RK-701 Inhibitor 98.04% 否
HY-RS01413 BCL11A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20529 Bcl11a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27038 Bcl11a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcl11a NCBI NCBI:53335
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z