1. Gene
  2. Elmo1 - engulfment and cell motility 1 Gene

Elmo1 - engulfment and cell motility 1 Gene

种属: Mus musculus

同用名: CED-12; 6330578D22Rik; C230095H21Rik

基因 ID: 140580 | 基因类型: protein coding

关于 Elmo1

功能概要

Predicted to enable SH3 domain binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Acts upstream of or within actin filament-based process and phagocytosis. Part of guanyl-nucleotide exchange factor complex. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; nervous system; retina; and vibrissa. Orthologous to human ELMO1 (engulfment and cell motility 1). [provided by Alliance of Genome Resources, Apr 2022]

Elmo1 基因产物(2)

mRNA Protein Name
NM_080288.2 NP_525027.1 engulfment and cell motility protein 1 isoform 3
NM_198093.3 NP_932761.1 engulfment and cell motility protein 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin filament-based process IDA
IDA: 通过直接分析推断
11595183 MGI
acts upstream of or within phagocytosis IDA
IDA: 通过直接分析推断
11595183 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
29949770 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
29949770 MGI
part of guanyl-nucleotide exchange factor complex IDA
IDA: 通过直接分析推断
11595183 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
29949770 MGI
is active in postsynapse IMP
IMP: 通过突变表型推断
29949770 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

engulfment and cell motility protein 1

engulfment and cell motility 1, ced-12 homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Elmo1 NCBI NCBI:9844