2. Gene
  3. Abcc3 - ATP binding cassette subfamily C member 3 Gene

Abcc3 - ATP binding cassette subfamily C member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Mlp2; Mrp3

基因 ID: 140668 | 基因类型: protein coding

关于 Abcc3

功能概要

Enables ABC-type bile acid transporter activity. Involved in several processes, including anion transport; response to estradiol; and response to lipopolysaccharide. Acts upstream of or within canalicular bile acid transport. Located in basolateral plasma membrane. Biomarker of several diseases, including bilirubin metabolic disorder (multiple); fatty liver disease (multiple); hepatocellular carcinoma; hyperprolactinemia; and kidney disease (multiple). Orthologous to human ABCC3 (ATP binding cassette subfamily C member 3). [provided by Alliance of Genome Resources, Apr 2022]

Abcc3 基因产物(1)

mRNA Protein Name
NM_080581.2 NP_542148.2 ATP-binding cassette sub-family C member 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ABC-type bile acid transporter activity IDA
IDA: 通过直接分析推断
10644759 RGD
enables ATPase-coupled transmembrane transporter activity IDA
IDA: 通过直接分析推断
10362653 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bile acid and bile salt transport IMP
IMP: 通过突变表型推断
10644759 RGD
acts upstream of or within canalicular bile acid transport IDA
IDA: 通过直接分析推断
10362653 RGD
involved in monoatomic anion transmembrane transport IDA
IDA: 通过直接分析推断
11837698 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
16554369 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18505788 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18648771 RGD
involved in response to tetrachloromethane IEP
IEP: 通过表达模式推断
17544377 RGD
involved in transmembrane transport IMP
IMP: 通过突变表型推断
12909565 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
11897632 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
18698235 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATP-binding cassette sub-family C member 3

canalicular multispecific organic anion transporter 2

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

ATP-binding cassette, subfamily C (CFTR/MRP), member 3

MLP-2

MRP-like protein 2

multidrug resistance protein 3

multidrug resistance-associated protein 3

organic anion transporter

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00062 ABCC3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19977 Abcc3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26480 Abcc3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abcc3 NCBI NCBI:8714
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