1. Gene
  2. Myh7 - myosin, heavy polypeptide 7, cardiac muscle, beta Gene

Myh7 - myosin, heavy polypeptide 7, cardiac muscle, beta Gene

种属: Mus musculus

同用名: B-MHC; Myhcb; MyHC-I; Myhc-b; betaMHC; beta-MHC; myHC-beta; myHC-slow; MYH-beta/slow

基因 ID: 140781 | 基因类型: protein coding

关于 Myh7

功能概要

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and identical protein binding activity. Acts upstream of or within cardiac muscle hypertrophy in response to stress and transition between fast and slow fiber. Located in Z disc and stress fiber. Part of Myosin complex. Is expressed in several structures, including diaphragm; eye; heart; musculature; and somite. Human ortholog(s) of this gene implicated in cardiomyopathy (multiple); congenital heart disease (multiple); distal myopathy 1; and hyaline body myopathy (multiple). Orthologous to human MYH7 (Myosin heavy chain 7). [provided by Alliance of Genome Resources, Apr 2022]

Myh7 基因产物(2)

mRNA Protein Name
NM_001361607.1 NP_001348536.1 myosin-7
NM_080728.3 NP_542766.1 myosin-7
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cardiac muscle hypertrophy in response to stress IDA
IDA: 通过直接分析推断
24137001 MGI
acts upstream of or within transition between fast and slow fiber IDA
IDA: 通过直接分析推断
18978355 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
21126233 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
25139234 MGI
located in myofibril IDA
IDA: 通过直接分析推断
9884344 MGI
part of myosin complex IDA
IDA: 通过直接分析推断
8482409 MGI
located in stress fiber IDA
IDA: 通过直接分析推断
21126233 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

myosin-7

myosin heavy chain 7

myosin heavy chain, cardiac muscle, fetal

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Myh7 NCBI NCBI:4625