2. Gene
  3. Acsl1 - acyl-CoA synthetase long-chain family member 1 Gene

Acsl1 - acyl-CoA synthetase long-chain family member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Acs; Acas; FACS; Acas1; Facl2; LACS1; LACS 1

基因 ID: 14081 | 基因类型: protein coding

关于 Acsl1

功能概要

The protein encoded by this gene belongs to a family of acyl coenzyme A synthetase proteins, which convert long chain fatty acids to acyl CoA products via an ATP-dependent pathway. This enzyme is enriched in heart, liver and adipose tissue, where it functions in lipid synthesis and mitochondrial and peroxisomal beta-oxidation. In addition, it is expressed in monocytes and macrophages where it appears to have a functionally distinct role in mediating inflammatory and innate immune responses. A pseudogene of this gene is found on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Acsl1 基因产物(4)

mRNA Protein Name
NM_001302163.1 NP_001289092.1 long-chain-fatty-acid--CoA ligase 1
NM_007981.4 NP_032007.2 long-chain-fatty-acid--CoA ligase 1
NM_001302163.1 NP_001289092.1 long-chain-fatty-acid--CoA ligase 1
NM_007981.4 NP_032007.2 long-chain-fatty-acid--CoA ligase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein serine/threonine kinase activator activity IGI
IGI: 通过遗传相互作用推断
20667975 MGI
enables protein serine/threonine kinase activator activity IMP
IMP: 通过突变表型推断
20667975 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adiponectin-activated signaling pathway IMP
IMP: 通过突变表型推断
20667975 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
20620995 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

long-chain-fatty-acid--CoA ligase 1

acetate-CoA ligase

acetyl-CoA synthetase

acetyl-Coenzyme A synthetase 1 (ADP forming)

arachidonate--CoA ligase

fatty acid Coenzyme A ligase, long chain 2

long-chain acyl-CoA synthetase 1

phytanate--CoA ligase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00200 ACSL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16255 Acsl1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24003 Acsl1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acsl1 NCBI NCBI:2180
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