1. Gene
  2. Ccn2 - cellular communication network factor 2 Gene

Ccn2 - cellular communication network factor 2 Gene

种属: Mus musculus

同用名: Ctgf; Hcs24; Fisp12; fisp-12

基因 ID: 14219 | 基因类型: protein coding

关于 Ccn2

功能概要

Enables heparin binding activity and Integrin binding activity. Acts upstream of or within several processes, including cartilage condensation; cell surface receptor signaling pathway; and chondrocyte proliferation. Located in extracellular matrix and extracellular region. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; sensory organ; and skeleton. Orthologous to human CCN2 (cellular communication network factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ccn2 基因产物(1)

mRNA Protein Name
NM_010217.2 NP_034347.2 CCN family member 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparin binding IDA
IDA: 通过直接分析推断
9184077 MGI
enables integrin binding IDA
IDA: 通过直接分析推断
10446209 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within angiogenesis IDA
IDA: 通过直接分析推断
10082563 MGI
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
12736220 MGI
acts upstream of or within cartilage condensation IDA
IDA: 通过直接分析推断
15305294 MGI
acts upstream of or within cell migration IDA
IDA: 通过直接分析推断
10082563 MGI
acts upstream of or within cell-matrix adhesion IDA
IDA: 通过直接分析推断
9184077 MGI
acts upstream of or within chondrocyte differentiation IDA
IDA: 通过直接分析推断
15305294 MGI
acts upstream of or within chondrocyte proliferation IMP
IMP: 通过突变表型推断
18597638 MGI
acts upstream of or within connective tissue development IMP
IMP: 通过突变表型推断
23839921 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
9184077 MGI
acts upstream of or within integrin-mediated signaling pathway IDA
IDA: 通过直接分析推断
10082563 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
18213577 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: 通过突变表型推断
18597638 MGI
acts upstream of or within ossification IMP
IMP: 通过突变表型推断
11237711 MGI
acts upstream of or within reactive oxygen species metabolic process IDA
IDA: 通过直接分析推断
19364818 MGI
acts upstream of or within regulation of chondrocyte differentiation IMP
IMP: 通过突变表型推断
18597638 MGI
acts upstream of or within tissue homeostasis IMP
IMP: 通过突变表型推断
23839921 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
9184077 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
1888698 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

CCN family member 2

Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24)

cellular communication network factor 1

fibroblast inducible secreated protein

fibroblast inducible secreted protein

hypertrophic chondro

重组 Ccn2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72154 CCN2/CTGF Protein, Mouse (GST) P29268 (Q26-Y344) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccn2 NCBI NCBI:1490
Rattus norvegicus Ccn2 NCBI NCBI:64032
Macaca mulatta Ccn2 NCBI NCBI:714520