2. Gene
  3. Xrcc6 - X-ray repair complementing defective repair in Chinese hamster cells 6 Gene

Xrcc6 - X-ray repair complementing defective repair in Chinese hamster cells 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ku70; 70kDa; G22p1

基因 ID: 14375 | 基因类型: protein coding

关于 Xrcc6

功能概要

Enables double-stranded DNA binding activity. Involved in positive regulation of lymphocyte differentiation. Acts upstream of or within DNA metabolic process; positive regulation of neurogenesis; and response to ionizing radiation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; early conceptus; gonad; liver lobe; and telencephalon ventricular layer. Orthologous to human XRCC6 (X-ray repair cross complementing 6). [provided by Alliance of Genome Resources, Apr 2022]

Xrcc6 基因产物(3)

mRNA Protein Name
NM_001411249.1 NP_001398178.1 X-ray repair cross-complementing protein 6 isoform 1
NM_001411250.1 NP_001398179.1 X-ray repair cross-complementing protein 6 isoform 2
NM_010247.3 NP_034377.2 X-ray repair cross-complementing protein 6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
20150414 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12551933 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA damage response IMP
IMP: 通过突变表型推断
15979950 MGI
acts upstream of or within V(D)J recombination IMP
IMP: 通过突变表型推断
10716994 MGI
acts upstream of or within double-strand break repair IMP
IMP: 通过突变表型推断
11751629 MGI
acts upstream of or within double-strand break repair via nonhomologous end joining IMP
IMP: 通过突变表型推断
11751629 MGI
acts upstream of neurogenesis IMP
IMP: 通过突变表型推断
10716994 MGI
involved in positive regulation of lymphocyte differentiation IMP
IMP: 通过突变表型推断
32103174 MGI
acts upstream of or within positive regulation of neurogenesis IMP
IMP: 通过突变表型推断
10716994 MGI
acts upstream of or within response to ionizing radiation IMP
IMP: 通过突变表型推断
15979950 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12604618 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12604618 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

X-ray repair cross-complementing protein 6

5'-dRP/AP lyase Ku70

5'-deoxyribose-5-phosphate lyase Ku70

ATP-dependent DNA helicase 2 subunit 1

ATP-dependent DNA helicase II 70 kDa subunit

CTC box-binding factor 75 kDa subunit

CTC75

CTCBF

DNA repair protein XRCC6

Ku p70

ku autoantigen protei

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15901 XRCC6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19756 Xrcc6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26253 Xrcc6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Xrcc6 NCBI NCBI:2547
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